ArticlePediatric surgery international2020
When primary repair is not enough: a comparison of synthetic patch and muscle flap closure in congenital diaphragmatic hernia?
Article in Pediatric surgery international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Muscle flap repair vs. patch repair in reducing recurrence in congenital diaphragmatic hernia: systematic review with Meta-Analysis.Pediatric surgery international · 2026Pooled it
- A systematic review and meta-analysis of surgical morbidity of primary versus patch repaired congenital diaphragmatic hernia patients.Scientific reports · 2021Pooled it
- Article
- Surgical management of the diaphragmatic defect in congenital diaphragmatic hernia: a contemporary review.World journal of pediatric surgery · 2024Review
- Congenital Diaphragmatic Hernia: Perinatal Prognostic Factors and Short-Term Outcomes in a Single-Center Series.Children (Basel, Switzerland) · 2023Article
- Long-Term Outcomes of Congenital Diaphragmatic Hernia: Report of a Multicenter Study in Japan.Children (Basel, Switzerland) · 2022Article
- The Survivorship Bias in Congenital Diaphragmatic Hernia.Children (Basel, Switzerland) · 2022Article
- Genetically Modified Mouse Models of Congenital Diaphragmatic Hernia: Opportunities and Limitations for Studying Altered Lung Development.Frontiers in pediatrics · 2022Review
- Transuterine Fetal Tracheal Occlusion Model in Mice.Journal of visualized experiments : JoVE · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrimary closure is often inadequate for large congenital diaphragmatic hernia (CDH) and necessitates repair by prosthetic patch or autologous muscle flap. Our aim was to evaluate outcomes of open patch versus flap repair, specifically diaphragmatic reherniation.
methodsA retrospective review (IRB #2017-6361) was performed on all CDH patients repaired from 2005 to 2016 at a single academic children's hospital. Patients were excluded from final analysis if they had primary or minimally invasive repair, expired, or were lost to follow-up.
resultsOf 171 patients, 151 (88.3%) survived to discharge, 9 expired after discharge and 11 were lost to follow up, leaving 131 (86.8%) long-term survivors. Median follow-up was 5 years. Open repair was performed in 119 (90.8%) of which 28 (23.5%) underwent primary repair, 34 (28.6%) patch repair, and 57 (47.9%) flap repair. Overall, 6/119 (5%) patients reherniated, 1/28 (3.6%) in the primary group, 3/34 (8.8%) in the patch group, and 2/57 (3.5%) in the flap group. Comparing prosthetic patch to muscle flap repair, there was no significant difference in the number of patients who recurred nor time to reherniation (3 vs. 2, p = 0.295; 5.5 ± 0.00 months vs. 53.75 ± 71.06 months, p = 0.288). One patient in the patch group recurred twice.
conclusionsBoth muscle flap and patch repair of large CDH are feasible and durable with a relatively low risk of recurrence.
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