Evidence map›Paper›PMID 32130271›Full record

ArticlePloS one2020

The screening score of Mini Nutritional Assessment (MNA) is a useful routine screening tool for malnutrition risk in patients on maintenance dialysis.

Els Holvoet, Karsten Vanden Wyngaert, Amaryllis H Van Craenenbroeck, Wim Van Biesen, Sunny Eloot

Registry-linked trialOpen access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04507867 (Effect of a Nutritional Support System to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04507867 nacompletednot on this map

Effect of a Nutritional Support System to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III

TypeinterventionalSponsorAnahuac UniversityRan2020 to 2021Enrolled80ConditionsCOVID19, Diabetes Mellitus, Hypertension, ObesityArmsNutritional support system (NSS), Conventional nutritional support designed by hospital nutritionists
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Els HolvoetRenal Division, Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0003-4412-370X
Karsten Vanden WyngaertDepartment of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.ORCID 0000-0001-6063-9971
Amaryllis H Van CraenenbroeckDepartment of Nephrology, University Hospitals Leuven, Leuven, Belgium.
Wim Van BiesenRenal Division, Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-4782-5224
Sunny ElootRenal Division, Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMalnutrition is prevalent in patients on dialysis and is associated with morbidity and mortality. Nutritional status can be assessed by a variety of biochemical and physical parameters or nutritional assessment scores. Most of these methods are expensive or cumbersome to use and are not suitable for routine repetitive follow-up in dialysis patients. The Mini Nutritional Assessment (MNA) has a short form screening set (MNA-SF), which would be suitable as a screening tool, but has not been validated yet in dialysis patients. We aimed to assess whether the MNA is an appropriate tool for identifying nutritional problems in dialysis patients.

methodMNA, routine biochemistry, physical parameters, comorbidities were assessed in cross-sectional multicentric cohorts of hemodialysis and peritoneal dialysis patients with a longitudinal follow up of 2 years for mortality.

resultsIn this cohort of 216 patients, mortality was 27.3% at a follow up of 750±350 days. The mean MNA-SF score was 9.9±1.8, with 30.1%, 59.3% and 10.6% of patients categorized as having normal nutritional status, at risk for malnutrition and malnourished, respectively. The screening score was associated with mortality (HR 0.86, 95% CI 0.75-0.98 per point). With normal nutrition as reference, adjusted mortality was 2.50 (95% CI 1.16-5.37) and 3.89 (95% CI 1.48-10.13) for patients at risk for malnutrition and with malnutrition, respectively. After recalibrating the MNA full score for the specificity of some of its domains for dialysis patients, the MNA-SF had a good sensitivity and specificity for not being well nourished (0.95 and 0.63 respectively) in the full score, and a high negative predictive value (0.91).

conclusionThe MNA-SF is independently associated with 2 year mortality in dialysis patients. It has a high negative predictive value for excluding being at risk or having malnutrition in the full score. Therefore, it can be advocated as a screening tool for nutritional status in dialysis patients.

Indexed as

Mass ScreeningNutrition AssessmentRenal DialysisAdultAgedFemaleHumansLogistic ModelsMaleMalnutritionMultivariate AnalysisProportional Hazards ModelsRisk FactorsROC CurveSurveys and QuestionnairesSurvival Analysis

Identifiers

PMID32130271
PMCPMC7055863
OpenAlexW3010597265

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.