Evidence map›Paper›PMID 32130252›Full record

ArticlePloS one2020

Availability, cost and affordability of essential cardiovascular disease medicines in the south west region of Cameroon: Preliminary findings from the Cameroon science for disease study.

Anastase Dzudie, Epie Njume, Martin Abanda, Leopold Aminde, Ba Hamadou, Bonaventure Dzekem, Marcel Azabji, Marie Solange Doualla, Marcelin Ngowe, Andre P Kengne

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Anastase DzudieFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Epie NjumeClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.ORCID 0000-0002-1788-6958
Martin AbandaClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.
Leopold AmindeClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.
Ba HamadouFaculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon.
Bonaventure DzekemClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.
Marcel AzabjiFaculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon.
Marie Solange DouallaFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Marcelin NgoweFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Andre P KengneClinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.
Université de Yaoundé I · CMUniversity of Douala · CMSouth African Medical Research Council · ZAUniversity of Buea · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMore than 80% of premature deaths due to cardiovascular disease (CVD) occur in low- and middle-income countries. However, access to, and affordability of medications remain a challenge in these countries.

objectiveTo assess the availability, cost and affordability of essential cardiovascular medicines in the South West region of Cameroon.

methodsIn an audit of 63 medicine outlets, twenty-six essential medicines were surveyed using the World Health Organisation (WHO) /Health Action International methodology. Availability, costs and the ratio of the median price to the international reference price were evaluated in public, confessional, private facility medicine outlets, and community pharmacies. Affordability was assessed by calculating the number of days' wages it will cost the lowest-paid unskilled government worker to purchase a month worth of chronic treatment.

findingsAvailability ranged from 25.3% (public facility outlets) to 49.2% (community pharmacies) for all medicines. This was higher in urban and semi-urban compared to rural outlets. Cost of medicines was highest in community pharmacies and lowest in public facility outlets. Aspirin, digoxin, furosemide, hydrochlorothiazide and nifedipine were affordable (cost a day's wage or less). Medicines for heart failure and dyslipidaemia (beta blockers, angiotensin converting enzyme inhibitors and statins) required 2-5 days and 6-13 days wages respectively for one month of chronic treatment.

conclusionOverall availability of CVD essential medicines was lower than WHO recommendations, and medicines were largely unaffordable. While primary prevention is pivotal, improving availability and affordability of medicines especially for public facilities would provide additional benefit in curbing the CVD burden.

Indexed as

Costs and Cost AnalysisCameroonCardiovascular DiseasesDrugs, EssentialHealth Services AccessibilityHumansDrugs, Essential

Identifiers

PMID32130252
PMCPMC7055918
OpenAlexW3010484680

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.