Evidence map›Paper›PMID 32130178›Full record

ArticleJMIR research protocols2020

A Theoretically Based Mobile App to Increase Pre-Exposure Prophylaxis Uptake Among Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial.

Jeb Jones, Karen Dominguez, Rob Stephenson, Joanne D Stekler, Amanda D Castel, Leandro A Mena, Samuel M Jenness, Aaron J Siegler, Patrick S Sullivan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03763942 (Theoretically Based Mobile App to Increase PrEP Uptake Among MSM), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03763942 nacompletednot on this map

Theoretically Based Mobile App to Increase PrEP Uptake Among MSM

TypeinterventionalSponsorEmory UniversityRan2020 to 2023Enrolled658ConditionsHIV InfectionsArmsHealthMindr App, Control App
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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  15. Reply.Journal of acquired immune deficiency syndromes (1999) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jeb JonesDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-9165-1658
Karen DominguezDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-9860-3146
Rob StephensonDepartment of Systems, Populations and Leadership, School of Nursing, University of Michigan, Ann Arbor, MI, United States.ORCID https://orcid.org/0000-0002-9239-2640
Joanne D SteklerDivision of Allergy & Infectious Diseases, School of Medicine, University of Washington, Seattle, WA, United States.ORCID https://orcid.org/0000-0001-8064-3011
Amanda D CastelDepartment of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, Washington, DC, United States.ORCID https://orcid.org/0000-0002-9095-2413
Leandro A MenaDepartment of Population Health Science, John D Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS, United States.ORCID https://orcid.org/0000-0001-8994-6457
Samuel M JennessDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-8840-105X
Aaron J SieglerDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-5553-7540
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-7728-0587
Emory University · USMilken Institute · USUniversity of Michigan · USUniversity of Mississippi Medical Center · USUniversity of Washington · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Theoretically Based Mobile App to Increase PrEP Uptake Among MSMR01DA045612 · NIDA · EMORY UNIVERSITY · PI SULLIVAN, PATRICK SEAN · 2017 to 2021
$5.2M
EpiModel 2.0: Integrated Network Models for HIV/STI Prevention ScienceR01AI138783 · NIAID · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2018 to 2021
$3.0M
Modeling Antiretroviral-Based Prevention among MSM in the USR21MH112449 · NIMH · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2017 to 2018
$442k
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI138783NIDA NIH HHS R01 DA045612NIMH NIH HHS R21 MH112449
6 · The paper itself

Abstract

backgroundHealthMindr is a mobile phone HIV prevention app for men who have sex with men (MSM). In a previous pilot study, HealthMindr was found to be acceptable among users and to demonstrate preliminary effectiveness for increasing pre-exposure prophylaxis (PrEP) uptake among MSM. PrEP is a highly effective HIV prevention intervention; however, uptake remains low.

objectiveThe aim of this study will be to assess the efficacy of a mobile app for increasing PrEP uptake among MSM in the southern United States.

methodsIn this randomized controlled trial, we will assess the efficacy of HealthMindr for increasing PrEP uptake among MSM in the following three southern US cities: Atlanta, Georgia; Jackson, Mississippi; and Washington, DC. In total, 657 men will be recruited and randomized to intervention and control arms in a 2:1 ratio. Participants in the intervention arm will receive access to the full HealthMindr app, with information and resources about PrEP (eg, frequently asked questions, risk assessment tool, and PrEP provider locator), other HIV prevention information, ability to order free HIV/sexually transmitted infection test kits, and additional resources related to substance use and mental health. Participants in the control arm will use the HealthMindr app but will only have access to the study timeline and a message center to communicate with study staff. Participants will complete quarterly surveys to assess self-reported PrEP uptake over 12 months of follow-up. Self-reported PrEP uptake will be verified by dried blood spot testing and/or uploading a photograph of a PrEP prescription.

resultsParticipant recruitment began in January 2020.

conclusionsThis trial will determine whether the HealthMindr app can increase PrEP uptake among MSM in the southern United States.

trial registrationClinicalTrials.gov NCT03763942; https://clinicaltrials.gov/ct2/show/NCT03763942. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/16231.

Indexed as

electronic healthHIVmen who have sex with menmobile healthpre-exposure prophylaxis

Identifiers

PMID32130178
PMCPMC7060494
OpenAlexW3006940950

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.