Evidence map›Paper›PMID 32129937›Full record

ArticleMolecular oral microbiology2020

The S. mutans mntE gene encodes a manganese efflux transporter.

Joseph O'Brien, Alexander Pastora, Andrew Stoner, Grace Spatafora

Open access · greenAbstract read
In one paragraph

Article in Molecular oral microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Small regulatory RNAs are mediators of theJournal of bacteriology · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Manganese Stress Adaptation Mechanisms ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph O'BrienProgram in Molecular Biology & Biochemistry, Department of Biology, Middlebury College, Middlebury, VT, USA.ORCID 0000-0002-6571-8246
Alexander PastoraProgram in Molecular Biology & Biochemistry, Department of Biology, Middlebury College, Middlebury, VT, USA.ORCID 0000-0001-7447-5218
Andrew StonerProgram in Molecular Biology & Biochemistry, Department of Biology, Middlebury College, Middlebury, VT, USA.
Grace SpataforaProgram in Molecular Biology & Biochemistry, Department of Biology, Middlebury College, Middlebury, VT, USA.ORCID 0000-0003-2043-4853
Middlebury College · US

Funding

Investigating SloR virulence gene metalloregulation in Streptococcus mutansR01DE014711 · NIDCR · MIDDLEBURY COLLEGE · PI SPATAFORA, GRACE A. · 2004 to 2021
$4.1M
Investigating SloR virulence gene metalloregulation in S. mutans.R56DE014711 · NIDCR · MIDDLEBURY COLLEGE · PI SPATAFORA, GRACE A. · 2009 to 2009
$341k
NIDCR NIH HHS R01 DE014711NIDCR NIH HHS R56 DE014711
6 · The paper itself

Abstract

Streptococcus mutans is a colonizer of the human dentition, and under conditions of dysbiosis is the primary causative agent of dental caries. The pathogenic potential of S. mutans depends, in part, on its ability to regulate the transport of metal ions across the plasma membrane to maintain intracellular metal ion homeostasis. Research in our laboratory has focused on the Mn

Indexed as

Dental CariesStreptococcus mutansBacterial ProteinsGene Expression Regulation, BacterialHumansIonsManganeseBacterial ProteinsIonsManganesemanganese exportmetal ion homeostasisstreptococci

Identifiers

PMID32129937
PMCPMC8212816
OpenAlexW3009334577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.