ArticleeLife2020
ARL13B regulates Sonic hedgehog signaling from outside primary cilia.
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Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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58citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
What it found
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Who cites it
58 citing papers in PubMed, 86 citations in OpenAlex.
- A Novel Reporter Mouse for Astrocyte-Derived Extracellular Vesicles Reveals Enrichment of Cargo at Neuronal Mitochondria.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Article
- Loss of INPP5E affects photoreceptor outer segment membrane biogenesis in iPSC-derived human retinal organoids.Journal of cell science · 2026Article
- Compartmentalized Nutrient and Hormone Sensing in β-Cells: the Role of Primary Cilia.Physiology (Bethesda, Md.) · 2026Review
- In situ proteomics unveils specialized domains for extrasynaptic signaling on neuronal cilia.Science advances · 2026Article
- A novel reporter mouse for astrocyte-derived extracellular vesicles reveals trafficking of cargo to neuronal mitochondria.bioRxiv : the preprint server for biology · 2026Article
- Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA.Cellular & molecular biology letters · 2026Article
- Ciliary protein ARL13b detected on RBCs as a potential indicative biomarker of vaso-occlusive crisis and disease severity in SCD: a retrospective pilot study.Journal of sickle cell disease · 2026Article
- ARL13B-Cerulean rescues Arl13b-null mouse from embryonic lethality and reveals a role for ARL13B in spermatogenesis.Journal of cell science · 2025Article
- The RNA splicing factor PRPF8 is required for left-right organiser cilia differentiation and determination of cardiac left-right asymmetry via regulation ofbioRxiv : the preprint server for biology · 2025Article
- Ciliary ARL13B Is Essential for Vision and Morphogenesis of Cone Outer Segments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- ARL13B-Cerulean rescuesbioRxiv : the preprint server for biology · 2025Article
- Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle.Cell & bioscience · 2025Review
- Cilia directionality reveals a slow reverse movement of principal neurons for positioning and lamina refinement in the cerebral cortex.Development (Cambridge, England) · 2025Article
- Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression.Frontiers in cell and developmental biology · 2025Article
- Fine-Tuned Expression of Evolutionarily Conserved Signaling Molecules in theInternational journal of molecular sciences · 2024Article
- Utilization of automated cilia analysis to characterize novel INPP5E variants in patients with non-syndromic retinitis pigmentosa.European journal of human genetics : EJHG · 2024Article
- Mapping protein distribution in the canine photoreceptor sensory cilium and calyceal processes by ultrastructure expansion microscopy.bioRxiv : the preprint server for biology · 2024Article
- Primary cilia signaling in astrocytes mediates development and regional-specific functional specification.Nature neuroscience · 2024Article
- SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking.International journal of molecular sciences · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Eduardo D GiganteNeuroscience Graduate Program, Emory University School of Medicine, Atlanta, United States.ORCID 0000-0002-1486-5377
Megan R TaylorEmory College of Arts and Sciences, Emory University School of Medicine, Atlanta, United States.
Anna A IvanovaDepartment of Biochemistry, Emory University School of Medicine, Atlanta, United States.
Richard A KahnDepartment of Biochemistry, Emory University School of Medicine, Atlanta, United States.
Tamara CasparyDepartment of Human Genetics, Emory University School of Medicine, Atlanta, United States.ORCID 0000-0002-6579-7589
Emory University · US
Funding
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1MENNCF - Viral Vector CoreP30NS055077 · NINDS · EMORY UNIVERSITY · PI SEYFRIED, NICHOLAS THOMAS · 2008 to 2018
$6.8MTraining In Systems And Integrative Biology NeuroscienceT32NS096050 · NINDS · EMORY UNIVERSITY · PI Yoland Smith · 2016 to 2026
$3.9MMolecular mechanisms of ARF family GTPasesR35GM122568 · NIGMS · EMORY UNIVERSITY · PI KAHN, RICHARD A · 2017 to 2024
$3.7MGenetic Dissection of Signaling and CiliaR35GM122549 · NIGMS · EMORY UNIVERSITY · PI CASPARY, TAMARA J. · 2017 to 2021
$2.0MMechanisms underlying Joubert syndrome related brain malformationsR01NS090029 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTON, EVA S, CASPARY, TAMARA J. · 2015 to 2018
$1.9MDefining the relationship of ciliary Arl13b and SmoothenedF31NS106755 · NINDS · EMORY UNIVERSITY · PI GIGANTE, EDUARDO D. · 2019 to 2020
$91kNCATS NIH HHS UL1 TR002378NIGMS NIH HHS R35 GM122549NIGMS NIH HHS R35 GM122568NINDS NIH HHS F31 NS106755NINDS NIH HHS P30 NS055077NINDS NIH HHS R01 NS090029NINDS NIH HHS T32 NS096050
Abstract
ARL13B is a regulatory GTPase highly enriched in cilia. Complete loss of
Indexed as
Signal TransductionADP-Ribosylation FactorsAmino Acid SequenceAnimalsBase SequenceCiliaCRISPR-Cas SystemsEmbryonic DevelopmentGene EditingGene ExpressionHedgehog ProteinsMiceMice, KnockoutMutationPhenotypeADP-Ribosylation FactorsArl13b protein, mouseHedgehog ProteinsARL13Bcell biologyciliadevelopmental biologymousemouse developmentsonic hedgehog signaling
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.