Evidence map›Paper›PMID 32128946›Full record

ArticleHuman brain mapping2020

The developmental trajectory of fronto-temporoparietal connectivity as a proxy of the default mode network: a longitudinal fNIRS investigation.

Chiara Bulgarelli, Carina C J M de Klerk, John E Richards, Victoria Southgate, Antonia Hamilton, Anna Blasi

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Chiara BulgarelliDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.ORCID 0000-0002-6153-137X
Carina C J M de KlerkCentre for Brain and Cognitive Development, Birkbeck College, University of London, London, UK.
John E RichardsInstitute for Mind and Brain, Department of Psychology, University of South Carolina, Columbia, South Carolina.
Victoria SouthgateDepartment of Psychology, University of Copenhagen, Copenhagen, Denmark.
Antonia HamiltonInstitute of Cognitive Neuroscience, University College London, London, UK.
Anna BlasiDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
University College London · GBUniversity of Copenhagen · DKUniversity of Essex · GBUniversity of South Carolina · US

Funding

The development of sustained attention in infantsR01HD018942 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 1988 to 2021
$4.2M
The Neurodevelopmental MRI DatabaseR03HD091464 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 2017 to 2018
$128k
NICHD NIH HHS R01 HD018942NICHD NIH HHS R03 HD091464Wellcome TrustWellcome Trust 105628/Z/14/ZWellcome Trust 204770/Z/16/Z
6 · The paper itself

Abstract

The default mode network (DMN) is a network of brain regions that is activated while we are not engaged in any particular task. While there is a large volume of research documenting functional connectivity within the DMN in adults, knowledge of the development of this network is still limited. There is some evidence for a gradual increase in the functional connections within the DMN during the first 2 years of life, in contrast to other functional resting-state networks that support primary sensorimotor functions, which are online from very early in life. Previous studies that investigated the development of the DMN acquired data from sleeping infants using fMRI. However, sleep stages are known to affect functional connectivity. In the current longitudinal study, fNIRS was used to measure spontaneous fluctuations in connectivity within fronto-temporoparietal areas-as a proxy for the DMN-in awake participants every 6 months from 11 months till 36 months. This study validates a method for recording resting-state data from awake infants, and presents a data analysis pipeline for the investigation of functional connections with infant fNIRS data, which will be beneficial for researchers in this field. A gradual development of fronto-temporoparietal connectivity was found, supporting the idea that the DMN develops over the first years of life. Functional connectivity reached its maximum peak at about 24 months, which is consistent with previous findings showing that, by 2 years of age, DMN connectivity is similar to that observed in adults.

Indexed as

Cerebral CortexChild DevelopmentChild, PreschoolConnectomeDefault Mode NetworkFemaleHumansInfantLongitudinal StudiesMaleNerve NetSpectroscopy, Near-Infrareddefault mode networkdevelopmental trajectoryfNIRSfronto-temporoparietal connectivityfunctional connectivityinfantsresting-state

Identifiers

PMID32128946
PMCPMC7294062
OpenAlexW3009407170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.