ArticlePsycho-oncology2020
Illness uncertainty, coping, and quality of life among patients with prostate cancer.
Article in Psycho-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
74 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Care intervention on psychological outcomes among patients admitted to intensive care unit: an umbrella review of systematic reviews and meta-analyses.Systematic reviews · 2023Pooled it
- Psychological and spiritual interventions to enhance meaning in adults diagnosed with cancer: a systematic review with meta-analysis and meta-regression.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- The psychosocial experiences of human papillomavirus (HPV) positive oropharyngeal cancer patients following (chemo)radiotherapy: A systematic review and meta-ethnography.Psycho-oncology · 2022Pooled it
- Systematic review of illness uncertainty management interventions for cancer patients and their family caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- The Relationship Between Illness Uncertainty and Social Support Among Cancer Patients: A Meta-analysis.Cancer nursingPooled it
- Neoadjuvant pamiparib plus abiraterone and androgen deprivation therapy for high-risk/very high-risk localized prostate cancer: an open-label, single-arm, phase 2 study.Prostate cancer and prostatic diseases · 2026Trial
- Exploring the mediating role of active coping in reducing perceived stress among men with advanced prostate cancer: a randomized controlled trial of cognitive behavioral stress management.Journal of behavioral medicine · 2025Trial
- Low Social Well-Being in Advanced and Metastatic Prostate Cancer: Effects of a Randomized Controlled Trial of Cognitive Behavioral Stress Management.International journal of behavioral medicine · 2025Trial
- Effectiveness of proactive health interventions in reducing symptoms and enhancing self-efficacy and self-management in prostate cancer survivors: a randomized controlled trial.Journal of cancer survivorship : research and practice · 2025Trial
- Narrative medicine in patients with cancer during intravenous antiblastic therapy: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Psychometric properties of the Brief Mishel Uncertainty in illness scales for patients with advanced cancer and their family caregivers.BMC psychology · 2025Trial
- Effect of psychological intervention combined with feedback-based health education on lung cancer patients.Revista da Escola de Enfermagem da U S P · 2025Trial
- Occurrence of sensitive topics during ward round: an ancillary analysis of the BEDSIDE-OUTSIDE trial.BMJ open · 2023Trial
- Building a Natural Language Processing Augmented Information Support System to Enhance Supportive Care for Patients With Prostate Cancer and Families: User-Centered, Iterative Approach.Journal of medical Internet research · 2026Article
- "Don't be a hero, don't keep it a secret": understanding the lived experience of Chinese American patients with cancer through their expressive writing entries.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- 'What would happen if I die in a foreign country?': Cancer-related personal uncertainty and its implications for health equity among Indonesian migrant domestic workers.International journal for equity in health · 2026Article
- Access to innovation in oncology from patients' perspectives: a qualitative systematic review.EClinicalMedicine · 2026Article
- Article
- Suicide risk in prostate cancer patients: epidemiological trends and a predictive modeling.BMC psychiatry · 2026Article
- Relationships Between Fear of Cancer Recurrence, Unmet Healthcare Needs, and Quality of Life Among Thai Breast Cancer Survivors Post-Treatment.Healthcare (Basel, Switzerland) · 2026Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveIllness uncertainty is a significant source of psychological distress that affects cancer patients' quality of life (QOL). Mishel's uncertainty in illness theory (UIT) proposes that illness uncertainty influences an individual's use of coping strategies, and directly and indirectly influences their QOL. This study tested the relationships depicted in the adapted UIT in cancer patients.
methodsThis cross-sectional study is a secondary analysis of the baseline data from a randomized clinical trial (N = 263 prostate cancer patients). Patients were diagnosed with localized (64.6%), biochemical recurrent (12.6%), or advanced (22.8%) prostate cancer. Uncertainty, coping (avoidant and active coping strategies), and QOL (physical and mental well-being) were measured using the Mishel's uncertainty of illness scale, Brief COPE, and the Medical Outcomes Study 12-item short form (SF-12), respectively. We used path analysis to achieve the research aim.
resultsPatients' illness uncertainty directly, negatively influenced their physical well-being (P < .001) and mental well-being (P < .05). Patients' illness uncertainty was positively related to their avoidant coping strategies (P < .001). Patients' active and avoidant coping strategies influenced their mental well-being (P < .001). Uncertainty also negatively influenced mental well-being through avoidant coping strategies. The model had excellent fit to the data.
conclusionsOur findings have indicated the potential of improving QOL by decreasing illness uncertainty and reducing avoidant coping strategies. Future research is needed to better understand the complex relationships between illness uncertainty, coping strategies, and domains of QOL among patients with different types of cancer using longitudinal research.
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