Evidence map›Paper›PMID 32128821›Full record

ReviewPhotochemistry and photobiology2020

Photodynamic Therapy and Immunity: An Update.

Riddhi Falk-Mahapatra, Sandra O Gollnick

Open access · bronzeAbstract readReview
In one paragraph

Review in Photochemistry and photobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 176 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Special Issue "Molecular Advances in Oncological Photodynamic Therapy".International journal of molecular sciences · 2026
    Article
  15. Article
  16. Article
  17. Preclinical Evaluation of an Integrin αBioconjugate chemistry · 2025
    Article
  18. Article
  19. Review
  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Riddhi Falk-MahapatraDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY.
Sandra O GollnickDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY.ORCID 0000-0001-6493-9306
Roswell Park Comprehensive Cancer Center · US

Funding

StatisticsP01CA055791 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PANDEY, RAVINDRA K. · 1992 to 2019
$36.0M
Photodynamic Therapy (PDT) Mechanisms: Tumor ImmunityR01CA098156 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI GOLLNICK, SANDRA O. · 2003 to 2013
$3.6M
MULTIDISCIPLINARY APPROACHES TUMOR IMMUNOLOGYT32CA085183 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Scott I. Abrams · 2001 to 2026
$3.1M
NCI NIH HHS 5P01CA98156NCI NIH HHS P01 CA055791NCI NIH HHS R01 CA098156NIH HHS T32CA085183
6 · The paper itself

Abstract

Dr. Thomas Dougherty and his Oncology Foundation of Buffalo were the first to support my (S.O.G.) research into the effects of photodynamic therapy (PDT) on the host immune system. The small grant I was awarded in 2002 launched my career as an independent researcher; at the time, there were few studies on the importance of the immune response on the efficacy of PDT and no studies demonstrating the ability of PDT to enhance antitumor immunity. Over the last decades, the interest in PDT as an enhancer of antitumor immunity and our understanding of the mechanisms by which PDT enhances antitumor immunity have dramatically increased. In this review article, we look back on the studies that laid the foundation for our understanding and provide an update on current advances and therapies that take advantage of PDT enhancement of immunity.

Indexed as

PhotochemotherapyAnimalsHeterograftsHumansImmune SystemLightMiceOxygenPhotosensitizing AgentsOxygenPhotosensitizing Agents

Identifiers

PMID32128821
PMCPMC7293553
OpenAlexW3009426500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.