Evidence map›Paper›PMID 32128792›Full record

ReviewClinical pharmacology and therapeutics2020

An Introduction to Machine Learning.

Solveig Badillo, Balazs Banfai, Fabian Birzele, Iakov I Davydov, Lucy Hutchinson, Tony Kam-Thong, Juliane Siebourg-Polster, Bernhard Steiert, Jitao David Zhang

Abstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  19. Artificial intelligence in precision poultry farming: opportunities, challenges, and future features.Animal frontiers : the review magazine of animal agriculture · 2026
    Article
  20. Review

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Solveig BadilloPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0002-7563-111X
Balazs BanfaiPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0003-0422-7977
Fabian BirzelePharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0001-8744-9561
Iakov I DavydovPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0003-3510-3926
Lucy HutchinsonPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0002-3845-5460
Tony Kam-ThongPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0002-5300-9573
Juliane Siebourg-PolsterPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0002-1759-3223
Bernhard SteiertPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0002-1398-1624
Jitao David ZhangPharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.ORCID 0000-0002-3085-0909

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last few years, machine learning (ML) and artificial intelligence have seen a new wave of publicity fueled by the huge and ever-increasing amount of data and computational power as well as the discovery of improved learning algorithms. However, the idea of a computer learning some abstract concept from data and applying them to yet unseen situations is not new and has been around at least since the 1950s. Many of these basic principles are very familiar to the pharmacometrics and clinical pharmacology community. In this paper, we want to introduce the foundational ideas of ML to this community such that readers obtain the essential tools they need to understand publications on the topic. Although we will not go into the very details and theoretical background, we aim to point readers to relevant literature and put applications of ML in molecular biology as well as the fields of pharmacometrics and clinical pharmacology into perspective.

Indexed as

Models, TheoreticalCluster AnalysisHumansMachine LearningPharmacology, Clinical

Identifiers

PMID32128792
PMCPMC7189875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.