Evidence map›Paper›PMID 32128726›Full record

ArticlePharmacoEconomics2020

Modeling Heterogeneity in Patients' Preferences for Psoriasis Treatments in a Multicountry Study: A Comparison Between Random-Parameters Logit and Latent Class Approaches.

Marco Boeri, Daniel Saure, Alexander Schacht, Elisabeth Riedl, Brett Hauber

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in PharmacoEconomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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  10. Preferences of patients with chronic low back pain about nonsurgical treatments: Results of a discrete choice experiment.Health expectations : an international journal of public participation in health care and health policy · 2023
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  12. Artificial intelligence in breast cancer screening: primary care provider preferences.Journal of the American Medical Informatics Association : JAMIA · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Marco BoeriRTI Health Solutions, Health Preference Assessment, Forsyth House, Cromac Square, Belfast, BT2 8LA, UK. mboeri@rti.org.ORCID 0000-0001-7346-2132
Daniel SaureEli Lilly and Company, Bad Homburg, Germany.
Alexander SchachtEli Lilly and Company, Bad Homburg, Germany.
Elisabeth RiedlEli Lilly and Company, Vienna, Austria.
Brett HauberRTI Health Solutions, Health Preference Assessment, Research Triangle Park, NC, USA.
Eli Lilly (Germany) · DERTI Health Solutions · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEither a random-parameters logit (RPL) or latent class (LC) model can be used to model or explain preference heterogeneity in discrete-choice experiment (DCE) data. The former assumes continuous distribution of preferences across the sample, while the latter assumes a discrete distribution. This study compared RPL and LC models to explore preference heterogeneity when analyzing patient preferences for psoriasis treatments.

methodsUsing DCE data collected from respondents with moderate-to-severe plaque psoriasis, we calculated and compared preference weights derived from RPL and LC models. We then compared how RPL and LC explain preference heterogeneity by exploring differences across subgroups defined by observed characteristics (i.e., country, age, gender, marital status, and psoriasis severity).

resultsWhile RPL and LC models resulted in the same mean preference weights, different preference-heterogeneity patterns emerged from the two approaches. In both models, country of residence and self-reported disease severity could be linked to systematic differences in preferences. The RPL also identified gender and marital status, but not age, as sources of heterogeneity; the LC membership probability model indicated that age was a significant factor, but not gender or marital status.

conclusionsUsing data from a psoriasis patient survey to compare two widely used methods for exploring heterogeneity identified differences in results between stated-preferences: subgroup analysis in the RPL model and inclusion of subgroup characteristics in the class membership probability function of the LC model. Researchers should model data using the most adaptable approach to address the initial study question.

Indexed as

Choice BehaviorAdultAge FactorsCross-Sectional StudiesFemaleHumansLatent Class AnalysisLogistic ModelsMaleMiddle AgedPatient PreferencePsoriasisSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID32128726
OpenAlexW3009575927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.