Evidence map›Paper›PMID 32128709›Full record

ReviewMolecular biology reports2020

Stem cell therapy: old challenges and new solutions.

Carmela Rita Balistreri, Elena De Falco, Antonella Bordin, Olga Maslova, Alexander Koliada, Alexander Vaiserman

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Biomarkers in Heart Failure: A Review and a Wish.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Frontiers in bioengineering and biotechnology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Hydrogel Microparticles for Bone Regeneration.Gels (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Stem Cell Therapy in Children with Traumatic Brain Injury.International journal of molecular sciences · 2023
    Review
  15. Review
  16. A Particular Focus on the Prevalence ofInternational journal of molecular sciences · 2023
    Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Carmela Rita BalistreriDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Palermo, Italy. carmelarita.balistreri@unipa.it.ORCID http://orcid.org/0000-0002-5393-1007
Elena De FalcoDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Antonella BordinDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Olga MaslovaNational University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine.ORCID http://orcid.org/0000-0002-9372-896X
Alexander KoliadaD.F. Chebotarev Institute of Gerontology, NAMS, Kyiv, Ukraine.
Alexander VaisermanD.F. Chebotarev Institute of Gerontology, NAMS, Kyiv, Ukraine.ORCID http://orcid.org/0000-0003-0597-0439
D.F. Chebotarev Institute of Gerontology · UAClinica Mediterranea · ITNational University of Life and Environmental Sciences of Ukraine · UASapienza University of Rome · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell therapy (SCT), born as therapeutic revolution to replace pharmacological treatments, remains a hope and not yet an effective solution. Accordingly, stem cells cannot be conceivable as a "canonical" drug, because of their unique biological properties. A new reorientation in this field is emerging, based on a better understanding of stem cell biology and use of cutting-edge technologies and innovative disciplines. This will permit to solve the gaps, failures, and long-term needs, such as the retention, survival and integration of stem cells, by employing pharmacology, genetic manipulation, biological or material incorporation. Consequently, the clinical applicability of SCT for chronic human diseases will be extended, as well as its effectiveness and success, leading to long-awaited medical revolution. Here, some of these aspects are summarized, reviewing and discussing recent advances in this rapidly developing research field.

Indexed as

HumansRegenerative MedicineStem CellsStem Cell Transplantation3D systemsBio-nanotechnologyBioprintingExosomesRegenerative medicineStem cell therapy

Identifiers

PMID32128709
OpenAlexW3009111093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.