ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2021
Laparoscopic Versus Open Appendectomy for Acute Appendicitis in Children: a Nationwide Retrospective Study on Postoperative Outcomes.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05511194 (Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Pooled it
- Impact of Trocar Position on Surgical Site Infection After Pediatric Laparoscopic Appendectomy: A 15-Year Single-Center Study.Medical sciences (Basel, Switzerland) · 2026Article
- Rethinking postoperative opioid use in pediatric appendectomy: a cross-cultural comparison between Japan and North America.Journal of anesthesia · 2026Article
- Comparative analysis of laparoscopic versus open surgery in appendicitis management.Bioinformation · 2026Article
- Jujube pit ingestion leading to ileal perforation and secondary acute appendicitis in a child: a case report.AME case reports · 2026Article
- Post appendectomy complications and associated factors among children in Amhara region, ethiopia: Multi-center retrospective follow up study.Langenbeck's archives of surgery · 2025Article
- Laparoscopic versus open appendicectomy performed by adult general surgeons in pre-teenage years children: a single-centre experience.Annals of the Royal College of Surgeons of England · 2025Article
- An interpretable and transparent machine learning framework for appendicitis detection in pediatric patients.Scientific reports · 2024Article
- Complication analysis in acute appendicitis, results from an international multicenter study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Observational
- The Outcome of Laparoscopic Versus Open Appendectomy in Childhood.Deutsches Arzteblatt international · 2024Article
- Clinical course in children with equivocal appendicitis on computed tomography: a retrospective cohort study.Annals of surgical treatment and research · 2023Article
- <Editors' Choice> Advantages of gasless single-port transumbilical extracorporeal laparoscopic-assisted appendectomy in the treatment of uncomplicated acute appendicitis in children in China: a multi-institutional retrospective study.Nagoya journal of medical science · 2022Article
- Clinical outcomes of locking polymeric clip for laparoscopic appendectomy in patients with appendicitis: a retrospective comparison with loop ligature.Annals of coloproctology · 2022Article
- Laparoscopic Appendectomy: A Safe and Definitive Solution for Suspected Appendicitis.Visceral medicine · 2021Article
- Article
- Outcomes after appendectomy in children with acute appendicitis treated at a tertiary paediatric centre: results from a retrospective cohort study.Langenbeck's archives of surgery · 2021Article
- Laparoscopic Appendectomy versus Open Surgery.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOur aim was to compare postoperative outcomes of laparoscopic and open appendectomies for acute appendicitis in children under the circumstance of widespread use of laparoscopic surgery.
methodThis study included data on laparoscopic and open appendectomies in children with acute appendicitis from the National Clinical Database, which is a Japanese nationwide surgical database, in 2015. The occurrence rates of complications within 30 days after the surgery and postoperative hospital stay were compared by univariate and multivariate analyses. p < 0.05 was considered statistically significant.
resultsThis study included 4489 appendectomies, of which 3166 surgeries (70.5%) were performed laparoscopically. Appendectomy was performed for complicated and uncomplicated appendicitis in 1765 (39.3%) and 2724 cases (60.7%), respectively. Postoperative complications within 30 days were observed in 246 operations (5.5%). Organ-space surgical site infection (SSI), deep wound SSIs, and superficial wound SSIs were observed in 2.3%, 1.0%, and 2.4% of operations, respectively. On multivariate analysis, the incidence of postoperative complications (odds ratio 1.21, 95% CI 0.90-1.64, p = 0.207) and the length of hospital stay (median 4 days in both groups, p = 0.835) were not significantly different between patients who underwent laparoscopic or open appendectomy. Subgroup analysis in complicated and uncomplicated appendicitis cases also demonstrated no significant differences in the incidence of postoperative complications between those who underwent laparoscopic or open appendectomy.
conclusionThis study suggested that the occurrence of postoperative complication and the length of hospital stay in pediatric patients who underwent laparoscopic appendectomy are similar with those in pediatric patients who underwent open appendectomy for acute appendicitis.
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