ReviewHeart failure reviews2021
Right ventricular involvement in cancer therapy-related cardiotoxicity: the emerging role of strain echocardiography.
Review in Heart failure reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Clinical Applications of Right Ventricular Strain by Two-Dimensional Speckle-Tracking Echocardiography.Echocardiography (Mount Kisco, N.Y.) · 2026Review
- Early Divergent Cardiac Adaptation After Hematopoietic Stem Cell Transplantation: A Multimodal Echocardiographic and Electrocardiographic Study.Diagnostics (Basel, Switzerland) · 2026Article
- Imaging in Cardio-Oncology: Role of Novel Echo Parameters in Breast Cancer and Gynecologic Malignancies.Current cardiology reports · 2026Review
- Beyond mean heart dose: quantitative impact of sub-structure spatial dosimetrics on subclinical myocardial strain in thoracic radiotherapy.Frontiers in cardiovascular medicine · 2026Article
- Chinese guideline for the clinical application of noninvasive imaging technology in accessing cancer therapy-related cardiovascular toxicity.Journal of geriatric cardiology : JGC · 2025Article
- Uncovering subclinical cardiotoxicity across chemotherapy phases in pediatric oncology.Frontiers in oncology · 2025Article
- Right ventricle involvement in patients with breast cancer treated with chemotherapy.Cardio-oncology (London, England) · 2024Article
- Superiority of left heart deformation in early anthracycline-related cardiac dysfunction detection.Open heart · 2023Article
- Right Ventricular Function in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia: From the CTOXALL Study.Cancers · 2023Article
- Watery cyst of the right ventricle: a case description.Quantitative imaging in medicine and surgery · 2023Article
- Nuclear medicine in the assessment and prevention of cancer therapy-related cardiotoxicity: prospects and proposal of use by the European Association of Nuclear Medicine (EANM).European journal of nuclear medicine and molecular imaging · 2023Article
- Diagnosis and Management of Cancer Treatment-Related Cardiac Dysfunction and Heart Failure in Children.Children (Basel, Switzerland) · 2023Review
- Right Ventricle and Radiotherapy: More Questions than Answers.Diagnostics (Basel, Switzerland) · 2023Review
- Article
- Systolic myocardial function measured by echocardiographic speckle-tracking and peak oxygen consumption in pediatric childhood cancer survivors-a PACCS study.Frontiers in cardiovascular medicine · 2023Article
- Right Ventricular Longitudinal Strain in Patients with Heart Failure.Diagnostics (Basel, Switzerland) · 2022Review
- Early detection of immune checkpoint inhibitor-related subclinical cardiotoxicity: A pilot study by using speckle tracking imaging and three-dimensional echocardiography.Frontiers in cardiovascular medicine · 2022Article
- Article
- Cardiotoxicity Monitoring in Patients With Cancer: Focus on Safety and Clinical Relevance.JCO oncology practice · 2021Article
- Cardiotoxicity of anthracycline-free targeted oncological therapies in HER2-positive breast cancer.Oncology letters · 2021Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The involvement of the right ventricle (RV) in various cardiovascular pathologies is usually explored and demonstrated after thorough research of the left ventricle (LV). This is also true in cardio-oncology, where multimodality imaging with cardiac magnetic resonance and nuclear imaging is essential, but echocardiography plays pivotal role in everyday clinical practice. Chemotherapy and radiotherapy effect on RV has been studied mainly in breast cancer patients and survivors from childhood cancer. Right ventricular geometry and shape limit the ability of classical echocardiographic indices like RV ejection fraction (RVEF), RV fractional area change (FAC), and tricuspid annular plane systolic excursion (TAPSE) to identify reliably subtle changes in RV systolic function in cancer patients. The assessment of diastolic function of the RV in various timepoints during or after chemotherapy leads to conflicting results too. However, longitudinal strain of the RV (RV LS) seems to detect myocardial injury with consistent results. Remarkably, cardiotoxicity of the RV is identified by RV LS almost simultaneously with LV cardiotoxicity and with similar cutoff percent change suggesting the uniform effect of cancer and its treatments on myocardium. The prognostic value of cardiotoxic effects on the RV needs to be investigated by large prospective studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.