Evidence map›Paper›PMID 32128597›Full record

ArticleActa dermato-venereologica2020

Pilot Study of a Novel Therapeutic Approach for Refractory Advanced Stage Folliculotropic Mycosis Fungoides.

Christina A Del Guzzo, Neha N Jariwala, Paul L Haun, Kelly M MacArthur, Christen M Mowad, Elisabeth G Richard, Joseph P Holton, Alain H Rook

Open access · goldAbstract read
In one paragraph

Article in Acta dermato-venereologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Oral Isotretinoin and Its Uses in Dermatology: A Review.Drug design, development and therapy · 2023
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Christina A Del GuzzoDepartment of Dermatology, University of Pennsylvania, 19104 Philadelphia, USA. christina.delguzzo@pennmedicine.upenn.edu.
Neha N Jariwala
Paul L Haun
Kelly M MacArthur
Christen M Mowad
Elisabeth G Richard
Joseph P Holton
Alain H Rook
California University of Pennsylvania · USGeisinger Medical Center · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Folliculotropic mycosis fungoides is a variant of cutaneous T-cell lymphoma characterized as having a folliculocentric infiltrate of malignant T cells along with a worse prognosis in comparison to the epidermotropic variants. Patients with advanced forms of folliculotropic mycosis fungoides are often poorly responsive to both skin-directed as well as to systemic therapies. We report here a high response rate using a novel therapeutic regimen combining interferon gamma, isotretinoin in low dose and topical carmustine, and in some cases concomitant skin-directed therapies, among 6 consecutive patients with refractory folliculotropic mycosis fungoides with stages IB through IIIB who had previously failed both topical and systemic therapies. The potential mechanisms of this multimodality approach are discussed.

Indexed as

Lymphoma, T-Cell, CutaneousMycosis FungoidesSkin NeoplasmsHumansPilot ProjectsSkincarmustinecutaneous t-cell lymphomafolliculotropic mycosis fungoidesinterferon-gammaisotretinointherapeutic approach

Identifiers

PMID32128597
PMCPMC9175056
OpenAlexW3009451435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.