Trial reportAmerican journal of epidemiology2020
Effect of a Home Pregnancy Test Intervention on Cohort Retention and Pregnancy Detection: A Randomized Trial.
Trial report in American journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- "We adjusted for race": now what? A systematic review of utilization and reporting of race in American Journal of Epidemiology and Epidemiology, 2020-2021.Epidemiologic reviews · 2023Pooled it
- Pooled it
- Home pregnancy test sensitivity by test timing and cycle length with real-world use among pregnancy planners who conceived.Fertility and sterility · 2026Article
- Per- and polyfluoroalkyl substances, perceived stress, and miscarriage risk in a cohort of US Black women.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Lessons learned from longitudinal biomonitoring and birth cohort studies: informing the future of reproductive health research in Canada.Environmental health : a global access science source · 2026Article
- Racialized economic segregation in relation to fecundability in a preconception cohort study.Journal of urban health : bulletin of the New York Academy of Medicine · 2026Article
- A prospective study of semen quality and fecundability among North American couples planning pregnancy.Andrology · 2026Article
- Childhood adversity and time to pregnancy in a preconception cohort.American journal of epidemiology · 2024Article
- A prospective cohort study of preconception COVID-19 vaccination and miscarriage.Human reproduction (Oxford, England) · 2023Article
- Preconception Periodontitis and Risk of Spontaneous Abortion in a Prospective Cohort Study.American journal of epidemiology · 2023Article
- Association of male fatty acid intake with fecundability among couples planning pregnancy.Human reproduction (Oxford, England) · 2023Article
- Use of Chemical Hair Straighteners and Fecundability in a North American Preconception Cohort.American journal of epidemiology · 2023Article
- Associations between Residential Greenspace and Fecundability in a North American Preconception Cohort Study.Environmental health perspectives · 2023Article
- Preconception contraceptive use and miscarriage: prospective cohort study.BMJ medicine · 2023Article
- International Natural Procreative Technology Evaluation and Surveillance of Treatment for Subfertility (iNEST): enrollment and methods.Human reproduction open · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
We conducted a parallel, nonblinded randomized trial to assess whether offering home pregnancy tests (HPTs) to preconception cohort study participants influenced cohort retention or pregnancy detection. Pregnancy Study Online participants were female, aged 21-45 years, attempting pregnancy, and not using fertility treatment. At enrollment (2017-2018), 1,493 participants with 6 or fewer cycles of attempt time were randomly assigned with 50% probability to receive 12 Clearblue visual HPTs plus the standard protocol (n = 720) or the standard protocol alone (n = 773). Women completed bimonthly questionnaires for 12 months or until conception, whichever came first. In intent-to-treat analyses, retention (≥1 follow-up) was higher in the HPT arm (n = 598; 83%) than the standard protocol arm (n = 535 (69%); mean difference = 15%, 95% CI: 10, 19). Mean time at first pregnancy testing was identical in both arms (2 days before expected menses), as was mean gestational weeks at first positive pregnancy test (4 weeks). Conception was reported by 78% of women in the HPT arm and 75% in the standard protocol arm. Spontaneous abortion was reported by 21% in the HPT arm (mean gestational weeks = 7) and 21% in the standard protocol arm (mean gestational weeks = 6). Randomization of HPTs was associated with greater cohort retention but had little impact on incidence or timing of pregnancy detection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.