Evidence map›Paper›PMID 32128471›Full record

ArticleAPL bioengineering2020

Data-driven statistical modeling of the emergent behavior of biohybrid microrobots.

Eric J Leaman, Ali Sahari, Mahama A Traore, Brian Q Geuther, Carmen M Morrow, Bahareh Behkam

Abstract read
In one paragraph

Article in APL bioengineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eric J LeamanDepartment of Mechanical Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA.
Ali SahariSchool of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, Virginia 24061, USA.
Mahama A TraoreDepartment of Mechanical Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA.
Brian Q GeutherDepartment of Mechanical Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA.
Carmen M MorrowDepartment of Mechanical Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-agent biohybrid microrobotic systems, owing to their small size and distributed nature, offer powerful solutions to challenges in biomedicine, bioremediation, and biosensing. Synthetic biology enables programmed emergent behaviors in the biotic component of biohybrid machines, expounding vast potential benefits for building biohybrid swarms with sophisticated control schemes. The design of synthetic genetic circuits tailored toward specific performance characteristics is an iterative process that relies on experimental characterization of spatially homogeneous engineered cell suspensions. However, biohybrid systems often distribute heterogeneously in complex environments, which will alter circuit performance. Thus, there is a critically unmet need for simple predictive models that describe emergent behaviors of biohybrid systems to inform synthetic gene circuit design. Here, we report a data-driven statistical model for computationally efficient recapitulation of the motility dynamics of two types of

Identifiers

PMID32128471
PMCPMC7049295

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.