Evidence map›Paper›PMID 32128463›Full record

ArticleBioactive materials2020

Angiogenic peptide hydrogels for treatment of traumatic brain injury.

Xiaotang Ma, Agnieszka Agas, Zain Siddiqui, KaKyung Kim, Patricia Iglesias-Montoro, Jagathi Kalluru, Vivek Kumar, James Haorah

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Applications of Hydrogels in Emergency Therapy.Gels (Basel, Switzerland) · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Tough Gelatin Hydrogel for Tissue Engineering.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaotang MaDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Agnieszka AgasDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Zain SiddiquiDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
KaKyung KimDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Patricia Iglesias-MontoroDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Jagathi KalluruDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Vivek KumarDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
James HaorahDepartment of Biomedical Engineering, Center for Injury Bio-Mechanics, Materials and Medicine, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
New Jersey Institute of Technology · USRutgers, The State University of New Jersey · US

Funding

Peptide hydrogels for management and treatment of neovascular posterior segment diseasesR15EY029504 · NEI · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI KUMAR, VIVEK · 2019 to 2020
$508k
Mechanisms of Atherosclerosis in Alcohol IntakeR21AA022734 · NIAAA · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI HAORAH, JAMES · 2014 to 2015
$396k
NEI NIH HHS R15 EY029504NIAAA NIH HHS R21 AA022734
6 · The paper itself

Abstract

Traumatic brain injury (TBI) impacts over 3.17 million Americans. Management of hemorrhage and coagulation caused by vascular disruption after TBI is critical for the recovery of patients. Cerebrovascular pathologies play an important role in the underlying mechanisms of TBI. The objective of this study is to evaluate a novel regenerative medicine for the injured tissue after brain injury. We utilized a recently described synthetic growth factor with angiogenic potential to facilitate vascular growth in situ at the injury site. Previous work has shown how this injectable self-assembling peptide-based hydrogel (

Indexed as

AngiogenesisCerebrovascular injuryRegenerative medicineSelf-assembling peptide hydrogelsTraumatic brain injury

Identifiers

PMID32128463
PMCPMC7042674
OpenAlexW3004101080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.