Evidence map›Paper›PMID 32128433›Full record

ReviewLaryngoscope investigative otolaryngology2020

Prognostic factors in laryngeal squamous cell carcinoma.

Carol R Bradford, Alfio Ferlito, Kenneth O Devaney, Antti A Mäkitie, Alessandra Rinaldo

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Selective neck dissection of level IIB in cN0 laryngeal cancer: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
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  4. The histopathological spectrum of laryngeal epithelial neoplasia.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Carol R BradfordDepartment of Otolaryngology-Head and Neck Surgery University of Michigan Medical School Ann Arbor Michigan.ORCID https://orcid.org/0000-0002-2768-4532
Alfio FerlitoInternational Head and Neck Scientific Group Padua Italy.
Kenneth O DevaneyDepartment of Pathology, Henry Ford Allegiance Health Jackson Michigan.
Antti A MäkitieDepartment of Otorhinolaryngology-Head and Neck Surgery University of Helsinki and Helsinki University Hospital Helsinki Finland.
Alessandra RinaldoFormer Department of Otolaryngology-Head and Neck Surgery, University of Udine School of Medicine Udine Italy.
Henry Ford Allegiance Health · USKarolinska University Hospital · SEScientific Software International (United States) · USUniversity of Michigan · USUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current treatment results of laryngeal squamous cell carcinoma still remain modest. Various prognostic factors have been investigated and need to be included in the management decision making.

methodsWe reviewed the pertinent literature regarding host, tumor, and treatment factors as prognostic indicators that influence outcome in patients diagnosed with laryngeal squamous cell carcinoma.

resultsHost, tumor, and treatment factors all have an important impact upon an individual patient's prognosis with laryngeal squamous cell carcinoma, whereas staging systems only take into account tumor factors. There is much work yet to be done to establish reliable, independent biomarkers that predict survival and response to treatment.

conclusionsOptimal outcomes for an individual patient can be achieved when taking into account tumor, host, and treatment factors.

Indexed as

laryngeal squamous cell carcinomaoverall survivalprognostic factors

Identifiers

PMID32128433
PMCPMC7042656
OpenAlexW3001547747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.