Evidence map›Paper›PMID 32128328›Full record

ArticleOpen forum infectious diseases2019

Predicting Carbapenem-Resistant

Michael Y Lin, Michael J Ray, Serena Rezny, Erica Runningdeer, Robert A Weinstein, William E Trick

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael Y LinDepartment of Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Michael J RayDepartment of Medicine, Cook County Health, Chicago, Illinois, USA.
Serena ReznyIllinois Department of Public Health, Chicago, Illinois, USA.
Erica RunningdeerIllinois Department of Public Health, Chicago, Illinois, USA.
Robert A WeinsteinDepartment of Medicine, Rush University Medical Center, Chicago, Illinois, USA.
William E TrickDepartment of Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Funding

ACL HHS U54CK000481NCEZID CDC HHS U54 CK000161NCEZID CDC HHS U54 CK000481NCEZID CDC HHS U54 CK000607
6 · The paper itself

Abstract

backgroundTimely identification of patients likely to harbor carbapenem-resistant

methodsWe performed a case-control study using the Illinois hospital discharge database. From a 2014-2015 patient cohort, we defined cases as index adult patient hospital encounters with a positive CRE culture collected within the first 3 days of hospitalization, as reported to the Illinois XDRO registry; controls were all patient admissions from the same hospital and month. We split the data into training (~60%) and validation (~40%) sets and developed a logistic regression model to estimate coefficients for predictors of interest.

resultsWe identified 486 index cases and 340 005 controls. Independent risk factors for CRE at the time of admission were age, number of short-term acute care hospital (STACH) hospitalizations in the prior 365 days, mean STACH length of stay, number of long-term acute care hospital (LTACH) hospitalizations in the prior 365 days, mean LTACH length of stay, current admission to LTACH, and prior hospital admission with an infection diagnosis code. When applying the model to the validation data set, the area under the receiver operating characteristic curve was 0.84.

conclusionsA prediction model utilizing prior health care exposure information could discriminate patients who were likely to harbor CRE at the time of hospital admission.

Indexed as

antibiotic resistancecarbapenem resistanceprediction

Identifiers

PMID32128328
PMCPMC7047960

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.