Evidence map›Paper›PMID 32128249›Full record

ArticlePilot and feasibility studies2020

Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial.

Gonzalo Garcia Guerra, Ari Joffe, Cathy Sheppard, Krista Hewson, Irina A Dinu, Allan de Caen, Hsing Jou, Lisa Hartling, Sunita Vohra, Canadian Critical Care Trials Group

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03497559 (Pilot Randomized Controlled Trial on Music Use for Sedation In Critically Ill Children), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03497559 nacompletednot on this map

Pilot Randomized Controlled Trial on Music Use for Sedation In Critically Ill Children

TypeinterventionalSponsorUniversity of AlbertaRan2018 to 2019Enrolled60ConditionsMusic Therapy, Critical Care, Analgesia, Ventilators, MechanicalArmsMusic
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Gonzalo Garcia Guerra1Department of Pediatrics, University of Alberta, College Plaza 8215 112 St NW, Edmonton, AB T6G 1C9 Canada.ORCID 0000-0001-6407-0823
Ari Joffe1Department of Pediatrics, University of Alberta, College Plaza 8215 112 St NW, Edmonton, AB T6G 1C9 Canada.
Cathy Sheppard2Stollery Children's Hospital, Edmonton, AB Canada.
Krista Hewson3Department of Educational Psychology, University of Alberta, Edmonton, AB Canada.
Irina A Dinu4School of Public Health, University of Alberta, Edmonton, AB Canada.
Allan de Caen1Department of Pediatrics, University of Alberta, College Plaza 8215 112 St NW, Edmonton, AB T6G 1C9 Canada.
Hsing Jou1Department of Pediatrics, University of Alberta, College Plaza 8215 112 St NW, Edmonton, AB T6G 1C9 Canada.
Lisa Hartling1Department of Pediatrics, University of Alberta, College Plaza 8215 112 St NW, Edmonton, AB T6G 1C9 Canada.
Sunita Vohra1Department of Pediatrics, University of Alberta, College Plaza 8215 112 St NW, Edmonton, AB T6G 1C9 Canada.
Canadian Critical Care Trials Group
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStress induced by pain and anxiety is common in pediatric intensive care unit (PICU) patients. Sedation/analgesia in PICU is usually achieved through various analgesics and sedatives. Excessive use of these drugs can put patients at risk for hemodynamic/respiratory instability, prolonged ventilation, withdrawal, delirium, and critical illness polyneuromyopathy.The use of non-pharmacologic interventions has been recommended by sedation guidelines. However, non-pharmacological measures in PICU, including music and noise reduction, have been inadequately studied.

methodsThe Music Use for Sedation in Critically ill Children (MUSiCC trial) pilot study is an investigator-initiated, three-arm, randomized controlled trial (RCT) on the use of music for sedation in PICU. The main goal of the study is to demonstrate feasibility of a music trial in PICU and to obtain the necessary information to plan a larger trial. The study compares music versus noise cancelation versus control in sedated and mechanically ventilated children admitted to PICU. In the music group, children receive the music (modified classical music) three times a day for 30 min at a time. Music is delivered with noise cancelation headphones. The noise cancelation group receives the same intervention but with a no music (sham playlist). The control group receives usual care with no specific intervention. Children remain in the study until extubation or a maximum of 7 days. The primary outcomes of the study are feasibility and sedation/analgesia requirements. Secondary outcomes include change in vital signs before and during the intervention, ICU delirium, and adverse effects related to the intervention. The estimated sample size is 20 subjects per group for a total of 60 children. DISCUSSION: Despite being recommended by current guidelines, evidence to support the use of music in PICU is lacking. Music has the potential to reduce sedation requirements and their negative side effects. This pilot RCT will demonstrate feasibility and provide the necessary information to plan a larger trial focusing on the effectiveness of the intervention.

trial registrationThe study was registered at ClinicalTrials.gov (NCT03497559) on April 13, 2018.

Indexed as

AnalgesiaIntensive careMusicPediatricSedation

Identifiers

PMID32128249
PMCPMC7043021
OpenAlexW3011010449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.