Evidence map›Paper›PMID 32128192›Full record

ArticleClinical case reports2020

A hidden cause of infertility in hypothyroid patients.

Magdy Mohamed Allam, Hanaa Tarek El-Zawawy, Sherine Samir Barakat, Soha Magdy Ahmed, Rasha Noureldin M Saleh

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Association of methylenetetrahydrofolate reductase (Archives of endocrinology and metabolism
    Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Magdy Mohamed AllamInternal Medicine Department, Endocrinology Unit Alexandria University Student Hospital (AUSH) Alexandria Egypt.ORCID https://orcid.org/0000-0003-3178-0487
Hanaa Tarek El-ZawawyInternal Medicine Department Faculty of Medicine Alexandria University Alexandria Egypt.ORCID https://orcid.org/0000-0002-2778-7689
Sherine Samir BarakatInternal Medicine Department Haematology Unit Alexandria University Student Hospital (AUSH) Alexandria Egypt.
Soha Magdy AhmedInternal Medicine Department, Endocrinology Unit Alexandria University Student Hospital (AUSH) Alexandria Egypt.ORCID https://orcid.org/0000-0002-1807-9250
Rasha Noureldin M SalehClinical Pathology Department Faculty of Medicine Alexandria University Alexandria Egypt.ORCID https://orcid.org/0000-0001-5593-1345
Alexandria University · EGUniversity of East Anglia · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists after optimizing thyroid function.

Indexed as

5‐methyl tetrahydrofolateHashimoto's thyroiditishypothyroidisminfertilitymethylene tetrahydrofolate reductasemiscarriagepregnancy loss

Identifiers

PMID32128192
PMCPMC7044389
OpenAlexW2998869548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.