Evidence map›Paper›PMID 32128023›Full record

ArticleThe World Allergy Organization journal2020

IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper.

Ignacio J Ansotegui, Giovanni Melioli, Giorgio Walter Canonica, Luis Caraballo, Elisa Villa, Motohiro Ebisawa, Giovanni Passalacqua, Eleonora Savi, Didier Ebo, R Maximiliano Gómez and 38 more

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07750236 (The Effect of Watching Cartoons and Using a Stress Ball on Fear, Anxiety, Pain, and Satisfaction During Allergy Testing in Children), which is not on this map. Cited by 236 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
236citing papers in PubMed, 2 pooled it
38.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07750236 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Watching Cartoons and Using a Stress Ball on Fear, Anxiety, Pain, and Satisfaction During Allergy Testing in Children

TypeinterventionalSponsorTarsus UniversityRan2026 to 2027Enrolled90ConditionsChild Allergy, Anxiety, Fear, PainArmscartoon-watching group, stress ball group
3 · Its place in the literature

Who cites it

236 citing papers in PubMed, 2 syntheses or guidelines pooled it, 511 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

176 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

48 authors at 20 institutions in 25 countries.

Ignacio J AnsoteguiHospital Quironsalud Bizkaia, Bilbao-Erandio, Spain.
Giovanni MelioliDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Giorgio Walter CanonicaDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Personalized Medicine, Asthma and Allergy, Humanitas Research Hospital, Rozzano, Milan, Italy.
Luis CaraballoInstitute for Immunological Research, University of Cartagena, Cartagena, Colombia.
Elisa VillaAzienda Sanitaria Locale di Vercelli, S.C. Pneumologia, Vercelli, Italia.
Motohiro EbisawaClinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Sagamihara, Kanagawa, Japan.
Giovanni PassalacquaAllergy and Respiratory Diseases, IRCCS Policlinico San Martino, University of Genoa, Genoa, Italy.
Eleonora SaviOspedale Civile, Gossolengo, PC, Italy.
Didier EboDepartment of Immunology - Allergology - Rheumatology, Antwerp University Hospital, Antwerp University, Department Immunology and Allergology, AZ Jan Palfijn Gent, Ghent, Belgium.
R Maximiliano GómezUniversidad Católica de Salta, Fundación Ayre, Buenos Aires, Argentina.
Olga Luengo SánchezAllergy Section, Department of Internal Medicine, Vall d'Hebron University Hospital, Barcelona, Spain.
John J OppenheimerPulmonary & Allergy Associates, Denville, NJ, USA.
Erika Jensen-JarolimInstitute for Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, The Interuniversity Messerli Research Institute, University of Veterinary Medicine Vienna, Medical University Vienna, Vienna, Austria.
David A FischerFischer Medicine Professional Corporation, Barrie, Ontario, Canada.
Tari HaahtelaSkin and Allergy Hospital, University of Helsinki, Helsinki, Finland.
Martti AntilaClínica de Alergía, Sorocaba, São Paulo, Brazil.
Jean J BousquetMACVIA-France, Montpellier, France.
Victoria CardonaUniversitat Autónoma de Barcelona, Hospital Universitario Vall d'Hebron, Servicio de Medicina Interna, Sección de Alergología, Barcelona, Spain.
Wen Chin ChiangMount Elizabeth Medical Centre, Chiang Children's Allergy & Asthma Clinic, Singapore, Singapore.
Pascal M DemolyUniversity Hospital Montpellier, Montpellier, France.
Lawrence M DuBuskeImmunology Research Institute of New England, Gardner, MA, USA.
Marta Ferrer PugaThe Unidad de Educación Médica, Department of Medical Education, School of Medicine, Clinica Universitad de Navarra, Navarra, Spain.
Roy Gerth van WijkErasmus MC, Sector Allergologie, Rotterdam, the Netherlands.
Sandra Nora González DíazUniversidad Autónoma de Nuevo León, Hospital Universitario, Monterrey, Nuevo León, Mexico.
Alexei Gonzalez-EstradaDepartment of Allergy, Mayo Clinic, Jacksonville, FL, USA.
Edgardo JaresFemeca Femedica, Buenos Aires, Argentina.
Ayse Füsun KalpaklioğluKirikkale Universitesi, Tip Fakultesi, Kirikkale, Turkey.
Luciana Kase TannoHospital Sírio Libanês, University of São Paulo, São Paulo, Brazil.
Marek L KowalskiFaculty of Medicine, Department of Clinical Immunology & Allergy, Medical University of Łódź, Łódź, Poland.
Dennis K LedfordUniversity of South Florida College of Medicine, Tampa, FL, USA.
Olga Patricia Monge OrtegaAllergology Unit, San Juan de Dios Hospital, University of Costa Rica, San José, Costa Rica.
Mário Morais AlmeidaHospital CUF-Descobertas, Lisbon, Portugal.
Oliver PfaarDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Rhinology and Allergy, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany.
Lars K PoulsenGentofte University Hospital, Lab for Allergology, Allergy Clinic, Hellerup, Denmark.
Ruby PawankarNippon Medical School, Dept. of Otolaryngology, Tokyo, Japan.
Harald E RenzUniversity Hospital GI & MR GmbH, Institute of Laboratory Medicine & Pathology, Standort Marburg, Marburg, Germany.
Antonino G RomanoStallergenes, Rome, Italy.
Nelson A Rosário FilhoUniversity of Parana, Curitiba, PR, Brazil.
Lanny RosenwasserUniversity of Missouri at Kansas City, School of Medicine, Kansas City, MO, USA.
Mario A Sánchez BorgesCentro Médico Docente La Trinidad, Caracas, Venezuela.
Enrico ScalaExperimental Allergy Unit, Istituto Dermopatico dell'Immacolata, Rome, Italy.
Gian-Enrico SennaOspedale Civile Maggiore, Verona, Italy.
Juan Carlos SisulAllergy & Asthma Institute, Asunción, Paraguay.
Mimi L K TangRoyal Children's Hospital, Department of Allergy & Immunology, Parkville, Victoria, Australia.
Bernard Yu-Hor ThongTan Tock Seng Hospital, Deptartment of Rheumatology, Allergy & Immunology, Singapore, Singapore.
Rudolf ValentaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Robert A WoodJohns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.
Torsten ZuberbierCampus Charite Mitte, Klinik fur Dermatologie & Allergologie, Berlin, Germany.
Humanitas University · ITAntwerp University Hospital · BEBarrie Urology Group · CACentro Médico Docente La Trinidad · VECharité - Universitätsmedizin Berlin · DEClinica Universidad de Navarra · ESErasmus MC · NLGentofte Hospital · DKGuyra Paraguay · PYHospital do Desterro · PTHospital Quirónsalud Barcelona · ESInserm · FRIstituto Dermopatico dell'Immacolata · ITJohns Hopkins University · USKırıkkale University · TRMayo Clinic in Florida · USMedical University of Lodz · PLMount Elizabeth Hospital · SGNational Sagamihara Hospital · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both

Indexed as

AAAAI, American Academy of Allergy Asthma and ImmunologyABA, Allergen Bead ArrayACAAI, American College of Allergy Asthma and ImmunologyAEC, Allergen Exposure ChambersAIT, allergen immunotherapyAllergyAnti-IgE, Antibody against IgEAP, Alkaline PhosphataseAU/mL, Allergenic Units milliLiterBAT, Basophil Activation TestBAU/mL, Biologic Allergenic Units milliLiterCaFE, Calibrated Fluorescence EnhancementCBA, Cytometric Bead ArrayCCD, Cross-reactive Carbohydrate DeterminantsCDER, Center for Drug Evaluation and Research (USA)CL, ChemiluminescenceDBPCFC, Double-Blind Placebo-Controlled Food ChallengeDiagnostic strategiesEAACI, European Academy of Allergy and ImmunologyEIA, Enzyme Immune AssayELISA, Enzyme Linked Immuno Sorbent AnalysisEMEA, European MEdicine AgenciesENPP-3, EctoNucleotide Pyrophosphatase/Phosphodiesterase 3FACS, Fluorescence-Activated Cell SortingFcεRI, High affinity IgE receptorFDA, Food and Drug Administration (U.S. Department of Health and Human Services)FEIA, Fluorescent Enzyme ImmunoassaysH1, Histamine 1 receptorH2, Histamine 2 receptorHPO, Horseradish PeroxidaseIDT, Intradermal TestIgEIgE, immunoglobulin EIn vitro testsISAC, Immuno-Solid phase Allergen ChipIUIS, International Union of Immunological SocietiesIVD, in vitro diagnostic toolkUA/L, kilo Units of Allergen/Liter for allergen-specific IgE antibody assaysLAMP-3, Lysosomal-Associated Membrane ProteinmAb, Monoclonal AntibodyMBAD, Molecule Based Allergy DiagnosticsMRGPRX2, Mas-related G protein receptor 2NIH, National Institutes of Health (USA)NMBAs, NeuroMuscular Blocking AgentsNPA, Negative Percent AgreementNSAIDs, Non-Steroidal Anti-Inflammatory DrugspNPP, p-NitrophenylphosphatePPA, Positive Percent AgreementPPT, Prick-Prick TestRAST, Radio Allergo Sorbent TestSCAR, severe cutaneous adverse drug reactionssIgE, specific IgESkin testsSPT, Skin prick testw/v, weight /volume

Identifiers

PMID32128023
PMCPMC7044795
OpenAlexW3007562574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.