Evidence map›Paper›PMID 32127983›Full record

ArticleOpen access Macedonian journal of medical sciences2019

Cytotoxic Activity of BornUSU I towards T47D Breast Cancer Cells.

Nadiya Anandita Nasution, Urip Harahap, Ginda Haro, Hari Purnomo, Denny Satria

Abstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadiya Anandita NasutionDepartment of Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Urip HarahapDepartment of Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Ginda HaroDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Hari PurnomoDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia.
Denny SatriaDepartment of Biology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to determine cytotoxic activity of BornUSU I or Boronhafagama I (1,5-bis(4-hydroxyphenyl)-3-oxa-1,5-diaza-2,4-diboropentane-2,4-diol) as a boron derivate compounds which are boron neutron captured theraphy (BNCT) candidates.

methodsThe T47D cells were treated by BornUSU I, and Tamoxifen as a positive control. The in vitro study was using MTT method with the incubation period for 24h and 48h. All data were determined using viability of cells equation for showing each IC

resultsThe IC

conclusionThe results reveal that BornUSU I provide effective as anticancer, especially for breast cancer treatment.

Indexed as

BornUSU IBreast cancerCytotoxicityT47D cells

Identifiers

PMID32127983
PMCPMC7048330

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.