Evidence map›Paper›PMID 32127830›Full record

ArticleAfrican health sciences2019

Assessment of drug therapy problem and associated factors among adult hypertensive patients at Ayder comprehensive specialized hospital, Northern Ethiopia.

Asgedom Solomon Weldegebreal, Fekadu Tezeta, Atey Tesfay Mehari, Wubetu Gashaw, Kassa Tesfaye Dessale, Niriayo Yirga Legesse

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Article in African health sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
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13citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  7. Drug-Related Problems and Pharmacists' Interventions in Hypertensive Outpatients: A Multicenter Prospective Study in 3 Vietnamese Hospitals.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2023
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  8. Article
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  10. Review
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  12. Editorial.African health sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asgedom Solomon WeldegebrealClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Ethiopia.
Fekadu TezetaClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Ethiopia.
Atey Tesfay MehariClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Ethiopia.
Wubetu GashawClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Ethiopia.
Kassa Tesfaye DessaleClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Ethiopia.
Niriayo Yirga LegesseClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug-therapy problems(DTPs) among hypertensive patients can result in patient's morbidity and mortality. The main aim of this study was to assess drug therapy problem and associated factors among hypertensive patients.

methodsA hospital based cross sectional study was conducted. The data was collected from patients' medical charts and through interview. Drug therapy problem was categorized according to Cipolle methods of DTP classification. Thedata was analyzed using the Statistical Package for the Social Sciences (SPSS), version 21.

resultsA total of 241 patients were studied. The mean number of antihypertensive medications prescribed were 1.41±0.53. A total of 357 drug therapy problems(DTPs) were identified. From the patients studied,134(55.6%) had at least one evidence of drug therapy problem. Non adherence was the most commonly identified drug therapy problem occurred in (143(59.3%)) patients. Substance use (AOR=0.445, 95% CI= 0.227-0.870, p=0.018) and comorbidity (AOR= 2.099, 95% CI= 1.192-3.694, p=0.010) werethe predictors of DTP.

conclusionMore than half of the participants had evidence of onset drug therapy problem. Thus efforts that could boost antihypertensive compliance and minimizes substance use should be adopted to reduce patients's drug therapy problems.

Indexed as

Drug MonitoringAdultAgedAntihypertensive AgentsComorbidityCross-Sectional StudiesDose-Response Relationship, DrugEthiopiaFemaleHealth Knowledge, Attitudes, PracticeHumansHypertensionMaleMiddle AgedRisk FactorsSocioeconomic FactorsAntihypertensive AgentsassessmentdrugEthiopiaproblemtherapy

Identifiers

PMID32127830
PMCPMC7040299

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.