Evidence map›Paper›PMID 32127719›Full record

ArticleApplied physics letters2019

Accurate phase retrieval of complex 3D point spread functions with deep residual neural networks.

Leonhard Möckl, Petar N Petrov, W E Moerner

Abstract read
In one paragraph

Article in Applied physics letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  15. Adaptive optics for optical microscopy [Invited].Biomedical optics express · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leonhard MöcklDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0003-1387-886X
Petar N PetrovDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0002-3806-534X
W E MoernerDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.ORCID https://orcid.org/0000-0002-2830-209X

Funding

Single-Molecule Imaging for Cell Biology and Super-Resolution MicroscopyR35GM118067 · NIGMS · STANFORD UNIVERSITY · PI MOERNER, WILLIAM E · 2016 to 2025
$6.2M
NIGMS NIH HHS R35 GM118067
6 · The paper itself

Abstract

Phase retrieval, i.e., the reconstruction of phase information from intensity information, is a central problem in many optical systems. Imaging the emission from a point source such as a single molecule is one example. Here, we demonstrate that a deep residual neural net is able to quickly and accurately extract the hidden phase for general point spread functions (PSFs) formed by Zernike-type phase modulations. Five slices of the 3D PSF at different focal positions within a two micrometer range around the focus are sufficient to retrieve the first six orders of Zernike coefficients.

Identifiers

PMID32127719
PMCPMC7043838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.