Evidence map›Paper›PMID 32127600›Full record

ArticleScientific reports2020

Deep learning applied to hyperspectral endoscopy for online spectral classification.

Alexandru Grigoroiu, Jonghee Yoon, Sarah E Bohndiek

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexandru Grigoroiu *Department of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge, CB3 0HE, United Kingdom.
Jonghee Yoon *Department of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge, CB3 0HE, United Kingdom.
Sarah E BohndiekDepartment of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge, CB3 0HE, United Kingdom. seb53@cam.ac.uk.ORCID http://orcid.org/0000-0003-0371-8635
University of Cambridge · GB

Funding

Cancer Research UK 16267Cancer Research UK 21102
6 · The paper itself

Abstract

Hyperspectral imaging (HSI) is being explored in endoscopy as a tool to extract biochemical information that may improve contrast for early cancer detection in the gastrointestinal tract. Motion artefacts during medical endoscopy have traditionally limited HSI application, however, recent developments in the field have led to real-time HSI deployments. Unfortunately, traditional HSI analysis methods remain unable to rapidly process the volume of hyperspectral data in order to provide real-time feedback to the operator. Here, a convolutional neural network (CNN) is proposed to enable online classification of data obtained during HSI endoscopy. A five-layered CNN was trained and fine-tuned on a dataset of 300 hyperspectral endoscopy images acquired from a planar Macbeth ColorChecker chart and was able to distinguish between its 18 constituent colors with an average accuracy of 94.3% achieved at 8.8 fps. Performance was then tested on a set of images simulating an endoscopy environment, consisting of color charts warped inside a rigid tube mimicking a lumen. The algorithm proved robust to such variations, with classification accuracies over 90% being obtained despite the variations, with an average drop in accuracy of 2.4% being registered at the points of longest working distance and most inclination. For further validation of the color-based classification system, ex vivo videos of a methylene blue dyed pig esophagus and images of different disease stages in the human esophagus were analyzed, showing spatially distinct color classifications. These results suggest that the CNN has potential to provide color-based classification during real-time HSI in endoscopy.

Identifiers

PMID32127600
PMCPMC7054302
OpenAlexW3009426894

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.