Evidence map›Paper›PMID 32127556›Full record

ArticleScientific reports2020

YY1

Patrick W Darcy, Lisa K Denzin, Derek B Sant'Angelo

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy.Clinical reviews in allergy & immunology · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Patrick W DarcyChild Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA.
Lisa K DenzinGraduate School of Biomedical Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA.
Derek B Sant'AngeloGraduate School of Biomedical Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA. santandb@Rutgers.edu.
Rutgers, The State University of New Jersey · USJohnson University · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Immunobiology of NKT cell development and functionR01AI059739 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI SANT'ANGELO, DEREK B. · 2006 to 2010
$2.5M
The function of PLZF in innate T cellsR01AI083988 · NIAID · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SANT'ANGELO, DEREK B. · 2010 to 2014
$2.2M
PLZF expression in adipose resident natural killer T cellsR21AI159066 · NIAID · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI SANT'ANGELO, DEREK B. · 2021 to 2022
$431k
NCI NIH HHS P30 CA072720NIAID NIH HHS R01 AI059739NIAID NIH HHS R01 AI083988NIAID NIH HHS R21 AI159066
6 · The paper itself

Abstract

Co-expression of Yin Yang 1 (YY1) is required for the full function of the transcription factor, PLZF, which is essential for the development of natural killer T cell (NKT cell) effector functions. Discordant expression of YY1 and PLZF, therefore, might define NKT cell subsets with distinct effector functions. A subset of NKT cells was identified that expressed low levels of YY1. YY1

Indexed as

AnimalsCell Line, TumorInterleukin-10KineticsMice, Inbred C57BLNatural Killer T-CellsThymus GlandYY1 Transcription FactorInterleukin-10Yy1 protein, mouseYY1 Transcription Factor

Identifiers

PMID32127556
PMCPMC7054430
OpenAlexW3010298080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.