ArticleProceedings of the National Academy of Sciences of the United States of America2020
Embedded droplet printing in yield-stress fluids.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 86 citations in OpenAlex.
- Up-and-down transformable embedded ink writing strategy for soft 3D architectures.Nature communications · 2025Article
- Tuning collagen and collagen-alginate mechanics through extrusion bioprinting process parameters.RSC advances · 2025Article
- Gel-Based Suspension Medium Used in 3D Bioprinting for Constructing Tissue/Organ Analogs.Gels (Basel, Switzerland) · 2024Review
- Printed polymer platform empowering machine-assisted chemical synthesis in stacked droplets.Nature communications · 2024Article
- Voxelated bioprinting of modular double-network bio-ink droplets.Nature communications · 2024Article
- From yield stress to elastic instabilities: Tuning the extensional behavior of elastoviscoplastic fluids.PNAS nexus · 2024Article
- Review of Droplet Printing Technologies for Flexible Electronic Devices: Materials, Control, and Applications.Micromachines · 2024Review
- The microparticulate inks for bioprinting applications.Materials today. Bio · 2024Review
- A dive into the bath: embedded 3D bioprinting of freeformBiomaterials science · 2023Review
- Microcapillary cell extrusion deposition with picolitre dispensing resolution.Bio-design and manufacturing · 2023Article
- Fluid-Mediated Fabrication of Complex Assemblies.JACS Au · 2022Review
- Engineered assistive materials for 3D bioprinting: support baths and sacrificial inks.Biofabrication · 2022Review
- Computational Modeling and Experimental Characterization of Extrusion Printing into Suspension Baths.Advanced healthcare materials · 2022Article
- Microfluidics-enabled functional 3D printing.Biomicrofluidics · 2022Review
- Control of Drug-Excipient Particle Attributes with Droplet Microfluidic-based Extractive Solidification Enables Improved Powder Rheology.Pharmaceutical research · 2022Article
- Simulated filament shapes in embedded 3D printing.Soft matter · 2021Article
- The rheology of direct and suspended extrusion bioprinting.APL bioengineering · 2021Review
- On-demand modulation of 3D-printed elastomers using programmable droplet inclusions.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microfluidic tools and techniques for manipulating fluid droplets have become core to many scientific and technological fields. Despite the plethora of existing approaches to fluidic manipulation, non-Newtonian fluid phenomena are rarely taken advantage of. Here we introduce embedded droplet printing-a system and methods for the generation, trapping, and processing of fluid droplets within yield-stress fluids, materials that exhibit extreme shear thinning. This technique allows for the manipulation of droplets under conditions that are simply unattainable with conventional microfluidic methods, namely the elimination of exterior influences including convection and solid boundaries. Because of this, we believe embedded droplet printing approaches an ideal for the experimentation, processing, or observation of many samples in an "absolutely quiescent" state, while also removing some troublesome aspects of microfluidics including the use of surfactants and the complexity of device manufacturing. We characterize a model material system to understand the process of droplet generation inside yield-stress fluids and develop a nascent set of archetypal operations that can be performed with embedded droplet printing. With these principles and tools, we demonstrate the benefits and versatility of our method, applying it toward the diverse applications of pharmaceutical crystallization, microbatch chemical reactions, and biological assays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.