ArticleProceedings. Biological sciences2020
Insecticide exposure during brood or early-adult development reduces brain growth and impairs adult learning in bumblebees.
Article in Proceedings. Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 72 citations in OpenAlex.
- Sulfoxaflor reduces food intake and learning efficiency of solitary Osmia bicornis bees.Scientific reports · 2026Article
- When a bigger brain is better: The case of bee olfactory learning.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Micro-computed tomography of termite gut anatomy: effects of staining regime on resolvability.PeerJ · 2026Article
- Review
- Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model.Scientific reports · 2025Article
- Sub-lethal imidacloprid exposure leads to presynaptic and postsynaptic alterations.Research square · 2025Article
- Pesticide and Pathogen Exposure Causes Idiosyncratic Gene Expression Responses Across Four Diverse North American Bumble Bee Species.Molecular ecology · 2025Article
- Article
- Article
- Insect immunity in the Anthropocene.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Acute and chronic pesticide exposure trigger fundamentally different molecular responses in bumble bee brains.BMC biology · 2025Article
- Life Stage- and Sex-Specific Sensitivity to Nutritional Stress in a Holometabolous Insect.Ecology and evolution · 2025Article
- A novel insecticide impairs bumblebee memory and sucrose responsiveness across high and low nutrition.Royal Society open science · 2024Article
- Bumblebee Foraging Dynamics and Pollination Outcomes for Cherry Tomato and Pear Varieties in Northern China.Insects · 2024Article
- Natural variability in bee brain size and symmetry revealed by micro-CT imaging and deep learning.PLoS computational biology · 2023Article
- Anatomical study of the red flour beetle using synchrotron radiation X-ray phase-contrast micro-tomography.Journal of anatomy · 2023Review
- Expression of subunits of an insecticide target receptor varies across tissues, life stages, castes, and species of social bees.Molecular ecology · 2023Article
- Signatures of increasing environmental stress in bumblebee wings over the past century: Insights from museum specimens.The Journal of animal ecology · 2023Article
- Micro-CT and deep learning: Modern techniques and applications in insect morphology and neuroscience.Frontiers in insect science · 2023Review
- The flavonoid rutin protects the bumble bee Bombus impatiens against cognitive impairment by imidacloprid and fipronil.The Journal of experimental biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For social bees, an understudied step in evaluating pesticide risk is how contaminated food entering colonies affects residing offspring development and maturation. For instance, neurotoxic insecticide compounds in food could affect central nervous system development predisposing individuals to become poorer task performers later-in-life. Studying bumblebee colonies provisioned with neonicotinoid spiked nectar substitute, we measured brain volume and learning behaviour of 3 or 12-day old adults that had experienced in-hive exposure during brood and/or early-stage adult development. Micro-computed tomography scanning and segmentation of multiple brain neuropils showed exposure during either of the developmental stages caused reduced mushroom body calycal growth relative to unexposed workers. Associated with this was a lower probability of responding to a sucrose reward and lower learning performance in an olfactory conditioning test. While calycal volume of control workers positively correlated with learning score, this relationship was absent for exposed workers indicating neuropil functional impairment. Comparison of 3- and 12-day adults exposed during brood development showed a similar degree of reduced calycal volume and impaired behaviour highlighting lasting and irrecoverable effects from exposure despite no adult exposure. Our findings help explain how the onset of pesticide exposure to whole colonies can lead to lag-effects on growth and resultant dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.