Evidence map›Paper›PMID 32126232›Full record

ArticleBiochimica et biophysica acta. Biomembranes2020

Ligand-induced conformational changes in a SMALP-encapsulated GPCR.

Sarah J Routledge, Mohammed Jamshad, Haydn A Little, Yu-Pin Lin, John Simms, Alpesh Thakker, Corinne M Spickett, Roslyn M Bill, Tim R Dafforn, David R Poyner and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

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  11. Structure and function of proteins in membranes and nanodiscs.Biochimica et biophysica acta. Biomembranes · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sarah J RoutledgeLife and Health Sciences, Aston University, Birmingham B4 7ET, UK.
Mohammed JamshadSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Haydn A LittleSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Yu-Pin LinSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
John SimmsLife and Health Sciences, Aston University, Birmingham B4 7ET, UK.
Alpesh ThakkerLife and Health Sciences, Aston University, Birmingham B4 7ET, UK.
Corinne M SpickettLife and Health Sciences, Aston University, Birmingham B4 7ET, UK.
Roslyn M BillLife and Health Sciences, Aston University, Birmingham B4 7ET, UK.
Tim R DaffornSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address: t.r.dafforn@bham.ac.uk.
David R PoynerLife and Health Sciences, Aston University, Birmingham B4 7ET, UK. Electronic address: d.r.poyner@aston.ac.uk.
Mark WheatleyCentre for Sport, Exercise and Life Sciences, Alison Gingell Building, Faculty of Health and Life Sciences, Coventry University, Coventry CV1 2DS, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK. Electronic address: mark.wheatley@coventry.ac.uk.
Aston University · GBUniversity of Birmingham · GBCoventry University · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I019960/1Biotechnology and Biological Sciences Research Council BB/I020349/1Biotechnology and Biological Sciences Research Council BB/R016615/1Biotechnology and Biological Sciences Research Council BB/R016755/1
6 · The paper itself

Abstract

The adenosine 2A receptor (A

Indexed as

Hydrophobic and Hydrophilic InteractionsLigandsLipidsMaleatesPichiaProtein ConformationReceptor, Adenosine A2ASpectrometry, FluorescenceStyreneTriazinesTriazolesTryptophanLigandsLipidsMaleatesmaleic acidReceptor, Adenosine A2AStyreneTriazinesTriazolesTryptophanZM 241385Adenosine receptorFluorescenceGPCRSMALP

Identifiers

PMID32126232
PMCPMC7156913
OpenAlexW3008657009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.