ArticlePloS one2020
Preoperative prognostic nutritional index as an independent prognostic factor for resected ampulla of Vater cancer.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Predictive role of the prognostic nutritional index for long-term prognosis among patients undergoing pancreatoduodenectomy: a meta-analysis.BMC surgery · 2025Pooled it
- Muscle index, weight loss, and tumor type predict adjuvant therapy failure in periampullary cancer.Frontiers in nutrition · 2026Article
- Postoperative prognostic nutrition index predicts survival in patients with small bowel adenocarcinoma after surgical resection.Journal of the Chinese Medical Association : JCMA · 2024Article
- Prognostic Significance of Sarcopenia and Systemic Inflammatory Markers in Biliary Tract Cancer: A Retrospective Cohort Study.Journal of gastrointestinal cancer · 2024Article
- Value of Preoperative Hematological Parameters in the Prognosis of Gastric Cancer Patients Undergoing a Total Gastrectomy.Current medical science · 2022Article
- Effect of trimodal pre-rehabilitation on the rehabilitation of patients with gastrointestinal tumors in the perioperative period.American journal of translational research · 2022Article
- A combined prediction model for biliary tract cancer using the prognostic nutritional index and pathological findings: a single-center retrospective study.BMC gastroenterology · 2021Article
- The Relationship Between Prognostic Nutritional Index and All-Cause Mortality in Critically Ill Patients: A Retrospective Study.International journal of general medicine · 2021Article
- The role of prognostic nutritional index for clinical outcomes of gastric cancer after total gastrectomy.Scientific reports · 2020Article
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8 authors at 1 institution in 1 country.
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Abstract
introductionPrognostic nutritional index (PNI) reflects the nutritional and immunologic status of the patients. The clinical application of PNI is already well-known in various kinds of solid tumors. However, there is no study investigating the relationship between PNI and oncological outcome of the resected ampulla of Vater (AoV) cancer. MATERIALS AND
methodsFrom January 2005 to December 2012, the medical records of patients who underwent pancreaticoduodenectomy for pathologically confirmed AoV cancer were retrospectively reviewed. Long-term oncological outcomes were compared according to the preoperative PNI value.
resultA total of 118 patients were enrolled in this study. The preoperative PNI was 46.13±6.63, while the mean disease-free survival was 43.88 months and the mean disease-specific survival was 55.3 months. In the multivariate Cox analysis, initial CA19-9 (p = 0.0399), lymphovascular invasion (p = 0.0031), AJCC 8th N-stage (p = 0.0018), and preoperative PNI (p = 0.0081) were identified as significant prognostic factors for resected AoV cancer. The disease-specific survival was better in the high preoperative PNI group (≤48.85: 40.77 months vs. >48.85: 68.05 months, p = 0.0015). A highly accurate nomogram was developed based on four clinical components to predict the 1, 3, and 5-year disease-specific survival probability (C-index 0.8169, 0.8426, and 0.8233, respectively).
conclusionIn resected AoV cancer, preoperative PNI can play a significant role as an independent prognostic factor for predicting disease-specific survival.
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