Evidence map›Paper›PMID 32125825›Full record

ReviewACS nano2020

Nanocarriers for the Delivery of Medical, Veterinary, and Agricultural Active Ingredients.

Paul L Chariou, Oscar A Ortega-Rivera, Nicole F Steinmetz

Open access · greenAbstract readReview
In one paragraph

Review in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Nanoparticles in the Treatment of Renal Fibrosis.International journal of nanomedicine · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Advances in constructing biocompatible nanocarriers.Drug delivery and translational research · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Oscar A Ortega-RiveraORCID 0000-0002-0773-0677
Nicole F SteinmetzORCID 0000-0002-0130-0481
University of California San Diego · US

Funding

Dual-pronged nano-drug delivery using plant virus-like particles.R01CA224605 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Nicole Franziska Steinmetz · 2017 to 2026
$4.0M
Overcoming the immune-suppressive tumor microenvironment through in situ vaccination nanotechnology.U01CA218292 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIERING, STEVEN, STEINMETZ, NICOLE FRANZISKA · 2017 to 2021
$3.0M
A theranostic approach for risk stratification and intervention of deep vein thrombosis.R01HL137674 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEINMETZ, NICOLE FRANZISKA · 2017 to 2020
$2.3M
Diagnosis and longitudinal monitoring of metastatic prostate cancer through molecular MR imaging.R01CA202814 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEINMETZ, NICOLE FRANZISKA · 2016 to 2020
$2.0M
NCI NIH HHS R01 CA202814NCI NIH HHS R01 CA224605NCI NIH HHS U01 CA218292NHLBI NIH HHS R01 HL137674
6 · The paper itself

Abstract

Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active ingredients in medical, veterinary, or agricultural applications, particularly when such ingredients are unstable, sparingly soluble, or cause off-target effects. In this review, we highlight the diversity of nanocarrier materials and their key advantages compared to free active ingredients. We discuss current trends based on peer-reviewed research articles, patent applications, clinical trials, and the nanocarrier formulations already approved by regulatory bodies. Although most nanocarriers have been engineered to combat cancer, the number of formulations developed for other purposes is growing rapidly, especially those for the treatment of infectious diseases and parasites affecting humans, livestock, and companion animals. The regulation and prohibition of many pesticides have also fueled research to develop targeted pesticide delivery systems based on nanocarriers, which maximize efficacy while minimizing the environmental impact of agrochemicals.

Indexed as

Drug Delivery SystemsNanomedicineAnimalsDrug CarriersDrug CompoundingHumansNanoparticlesPesticidesDrug CarriersPesticidesagrochemical deliverycancerclinical trialsdrug deliverygene deliverynanocarriernanomedicinepest managementprecision farmingveterinary medicine

Identifiers

PMID32125825
PMCPMC8085836
OpenAlexW3010279508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.