Evidence map›Paper›PMID 32125680›Full record

ArticleInfection2020

Controversies in the therapeutic approach to congenital cytomegalovirus infection.

María Garrido-Barbero, Juan Arnaez, Alfredo Garcia-Alix

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

María Garrido-BarberoNeonatal Unit, Deparment of Pediatrics, University Hospital of Burgos, Avda Islas Baleares 3, 09006, Burgos, Spain.
Juan ArnaezNeonatal Unit, Deparment of Pediatrics, University Hospital of Burgos, Avda Islas Baleares 3, 09006, Burgos, Spain. juan.arnaez@neurologianeonatal.com.ORCID http://orcid.org/0000-0001-8883-5181
Alfredo Garcia-AlixNeNe Foundation, Madrid, Spain.
Hospital Universitario de Burgos · ESHospital Sant Joan de Déu Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of congenital cytomegalovirus infection is mandatory in cases with severe systemic and/or neurological involvement. However, some patients are paucisymptomatic, with very subtle systemic manifestations and/or minimal brain alterations. Current international guidelines do not clearly state whether these children should be treated, and this decision is not straightforward for clinicians. Of a small series of six infants with congenital cytomegalovirus infection admitted to our neonatal unit between 2015 and 2019, half showed paucisymptomatic neurological manifestations. In these cases, the determination of ß2-microglobulin in cerebrospinal fluid and magnetic resonance imaging aided in the decision-making concerning the therapeutic approach to follow.

Indexed as

Antiviral Agentsbeta 2-MicroglobulinBrainCytomegalovirusCytomegalovirus InfectionsFemaleHumansInfantInfant, NewbornMagnetic Resonance ImagingMaleSpainValganciclovirAntiviral Agentsbeta 2-MicroglobulinValganciclovirCongenital cytomegalovirusDecision-makingGuidelinesInfant

Identifiers

PMID32125680
OpenAlexW3009207304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.