Evidence map›Paper›PMID 32125668›Full record

Trial reportSports medicine (Auckland, N.Z.)2020

Effects of Autograft Types on Muscle Strength and Functional Capacity in Patients Having Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial.

Kasper Staghøj Sinding, Torsten Grønbech Nielsen, Lars Grøndahl Hvid, Martin Lind, Ulrik Dalgas

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sports medicine (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02173483 (Anterior Cruciate Ligament-reconstruction), which is not on this map. Cited by 38 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 6 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02173483 nacompletednot on this map

Anterior Cruciate Ligament-reconstruction: Quadriceps Tendon or Hamstrings Tendon? A Prospective Randomised Controlled Trial

TypeinterventionalSponsorAarhus University HospitalRan2014 to 2019Enrolled100ConditionsLigament, Laxity, Knee, Rupture of Anterior Cruciate LigamentArmsQuadriceps graft
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 6 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  17. Comparison of double bundle semitendinosus technique and pedicled quadriceps technique in patellar instability.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kasper Staghøj SindingDepartment of Sports Traumatology, Aarhus University Hospital, Aarhus, Denmark.
Torsten Grønbech NielsenDepartment of Sports Traumatology, Aarhus University Hospital, Aarhus, Denmark.
Lars Grøndahl HvidExercise Biology, Department of Public Health, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-3233-0429
Martin LindDepartment of Orthopedic Surgery, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-7204-813X
Ulrik DalgasExercise Biology, Department of Public Health, Aarhus University, Aarhus, Denmark. dalgas@ph.au.dk.ORCID http://orcid.org/0000-0003-4132-2789
Aarhus University Hospital · DKAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effects of different autograft types for anterior cruciate ligament reconstruction (ACL-R) on muscle function are sparsely investigated in randomized controlled trials. Our aim was to investigate the effects of quadriceps tendon autograft (QTB) vs. semitendinosus-gracilis autograft (StG) on thigh muscle strength and functional capacity, and a patient-reported outcome 1 year after ACL-R, and to compare the results to healthy controls.

methodsACL-R patients (n = 100) and matched controls (CON, n = 50) were recruited, with patients being randomly assigned to QTB (n = 50) or StG (n = 50) ACL-R. One year after ACL-R, bilateral knee extensor (KE) and flexor (KF) muscle strength (isometric, dynamic, explosive, limb symmetry index [LSI], hamstring:quadriceps ratio [HQ ratio]) were assessed by isokinetic dynamometry, along with functional capacity (single leg hop distance [SHD]) and a patient-reported outcome (International Knee Documentation Committee [IKDC] score).

resultsKE muscle strength of the operated leg was lower (9-11%) in QTB vs. StG as was KE LSI, while KF muscle strength was lower (12-17%) in StG vs. QTB as was KF LSI. HQ ratios were lower in StG vs. QTB. Compared with the controls, KE and KF muscle strength were lower in StG (10-22%), while KE muscle strength only was lower in QTB (16-25%). Muscle strength in the StG, QTB, and CON groups was identical in the non-operated leg. While SHD and IKDC did not differ between StG and QTB, SHD in both StG and QTB was lower than CON. The IKDC scores improved significantly 1 year following ACL-R for both graft types.

conclusionOne year after ACL-R, muscle strength is affected by autograft type, with StG leading to impairments of KE and KF muscle strength, while QTB results in more pronounced impairments of KE only. Functional capacity and patient-reported outcome were unaffected by autograft type, with the former showing impairment compared to healthy controls. CLINICAL TRIALS REGISTRATION NUMBER: NCT02173483.

Indexed as

AutograftsAdultAnterior Cruciate Ligament ReconstructionExercise TestFemaleHamstring MusclesHumansMaleMuscle StrengthPatient Reported Outcome MeasuresProspective StudiesQuadriceps MuscleTendonsYoung Adult

Identifiers

PMID32125668
OpenAlexW3009078955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.