Evidence map›Paper›PMID 32125611›Full record

ArticleBrain imaging and behavior2021

Altered static and dynamic voxel-mirrored homotopic connectivity in subacute stroke patients: a resting-state fMRI study.

Jing Chen, Dalong Sun, Yonghui Shi, Wei Jin, Yanbin Wang, Qian Xi, Chuancheng Ren

Abstract read
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In one paragraph

Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing Chen *Department of Neurology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Dalong Sun *Division of Gastroenterology, Department of Internal Medicine, Zhongshan Hospital Affiliated to Fudan University, Xuhui District, Shanghai, China.
Yonghui ShiDepartment of Neurology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Wei JinDepartment of Neurology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Yanbin WangDepartment of Radiology, Shanghai East Hospital, Tongji University, Shanghai, China.
Qian XiDepartment of Radiology, Shanghai East Hospital, Tongji University, Shanghai, China. 96125007@sina.com.
Chuancheng RenDepartment of Neurology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China. rccfns17@sina.com.

Funding

China National Funds for Distinguished Young Scientists 81301200Key Programme 81571277the academic leader training plan of Shanghai Pudong New Area health system PWRd2016-07the scientific research project of the Shanghai health and family planning committee 201740207
6 · The paper itself

Abstract

Sixty-four subacute stroke patients and 55 age-matched healthy controls (HCs) underwent a resting-state functional magnetic resonance imaging scan using an echo-planar imaging sequence and high-resolution sagittal T1-weighted images using a three-dimensional magnetization-prepared rapid gradient echo sequence. Static and dynamic voxel-mirrored homotopic connectivity (VMHC) was computed, respectively. The relationships between the clinical measures, including National Institutes of Health Stroke Scale (NIHSS), illness duration, Fugl-Meyer assessment for upper and lower extremities (FMA-total) and size of lesion volume, and the static/ dynamic VMHC variability alterations in stroke patients were calculated. The stroke patients showed significantly increased static VMHC in the corpus callosum, middle occipital gyrus and inferior parietal gyrus, and decreased static VMHC in the inferior temporal gyrus and precentral gyrus (PreCG) compared with those of HCs. For dynamic VMHC variability, increased dynamic VMHC variability in the inferior temporal gyrus and PreCG was detected in stroke patients relative to that in HCs. Correlation analysis exhibited that significant negative correlations were shown between the FMA scores and dynamic VMHC variability in PreCG. The present study suggests that combined static and dynamic VMHC could be helpful to evaluate the motor function of stroke patients and understand the intrinsic differences of inter-hemispheric coordination after stroke.

Indexed as

Magnetic Resonance ImagingStrokeCase-Control StudiesCorpus CallosumHumansParietal LobeFunctional connectivityResting-state fMRIStrokeVoxel-mirrored homotopic connectivity

Identifiers

PMID32125611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.