Evidence map›Paper›PMID 32125610›Full record

ArticleBrain imaging and behavior2021

Functional connectivity of thalamus in children with primary nocturnal enuresis: results from a resting-state fMRI study.

Anyi Zhang, Lichi Zhang, Mengxing Wang, Yiwen Zhang, Fan Jiang, Xingming Jin, Xiaoxia Du, Jun Ma

Abstract read
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In one paragraph

Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  9. Pathogenesis and brain functional imaging in nocturnal enuresis: A review.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anyi Zhang *Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong-Fang Road, 200127, Shanghai, People's Republic of China.
Lichi Zhang *Institute for Medical Imaging Technology, Shanghai Jiao Tong University, Shanghai, China.
Mengxing WangDepartment of Physics, Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, 3663 North Zhong-Shan Road, Shanghai, 200062, China.
Yiwen ZhangDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong-Fang Road, 200127, Shanghai, People's Republic of China.
Fan JiangDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong-Fang Road, 200127, Shanghai, People's Republic of China.
Xingming JinDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong-Fang Road, 200127, Shanghai, People's Republic of China.
Xiaoxia DuDepartment of Physics, Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, 3663 North Zhong-Shan Road, Shanghai, 200062, China. xxdu@phy.ecnu.edu.cn.
Jun MaDepartment of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong-Fang Road, 200127, Shanghai, People's Republic of China. majun@shsmu.edu.cn.
Shanghai Jiao Tong University · CNEast China Normal University · CN

Funding

Development of Science and Technology in Pu Dong District PKJ2017-Y06Science and Technology Commission of Shanghai Municipality 14JC1404600Science and Technology Commission of Shanghai Municipality 16411952800Science and Technology Commission of Shanghai Municipality 18411960200
6 · The paper itself

Abstract

Primary nocturnal enuresis (PNE) is characterized by a low cure rate and a high reoccurrence rate, since its underlying mechanism remains unclear. Based on the recent studies that thalamus plays an important role in waking up a sleeping person, here we further investigate the functional connectivity (FC) information between thalamus and other brain regions, in order to make better understanding of the PNE's pathogenesis. In this study, we enrolled 30 children diagnosed with PNE and 30 typically developing children that are age and sex matched, the thalamus-based FC estimates were extracted at the resting-state. Experiments showed that for children with PNE, there were four brain regions found with a reduced connection efficiency with thalamus, that were cerebellum posterior lobe, frontal lobe, parietal lobe and precentral gyrus. It can be concluded that these relevant regions might induce an arousal disorder, and therefore further lead to PNE. This finding also provides a new insight in the pathophysiology of PNE.

Indexed as

Magnetic Resonance ImagingNocturnal EnuresisBrainBrain MappingChildHumansThalamusArousalFunctional connectivityPrimary nocturnal enuresisResting-state functional magnetic resonance imagingThalamus

Identifiers

PMID32125610
OpenAlexW3009817287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.