Evidence map›Paper›PMID 32125447›Full record

ArticlePediatric radiology2020

Clinical evaluation of reconstruction and acquisition time for pediatric

Nicholas A Shkumat, Reza Vali, Amer Shammas

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  6. EANM procedural recommendations for managing the paediatric patient in diagnostic nuclear medicine.European journal of nuclear medicine and molecular imaging · 2023
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  11. International consensus on the use of [European journal of nuclear medicine and molecular imaging · 2021
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  12. Validation of Deep Learning-based Augmentation for ReducedRadiology. Artificial intelligence · 2021
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  14. Moving the goalposts while scoring-the dilemma posed by new PET technologies.European journal of nuclear medicine and molecular imaging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nicholas A ShkumatDepartment of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Suite 2175A, Toronto, ON, M5G 1X8, Canada. nicholas.shkumat@sickkids.ca.ORCID 0000-0002-7929-4587
Reza ValiDepartment of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Suite 2175A, Toronto, ON, M5G 1X8, Canada.
Amer ShammasDepartment of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Suite 2175A, Toronto, ON, M5G 1X8, Canada.
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectiveTo quantify the diagnostic performance of a block-sequential regularized expectation maximization (BSREM) tool and reduced effective counts in brain PET/CT for pediatric epilepsy patients on a digital silicon photomultiplier system. MATERIALS AND

methodsWe included 400 sets of brain PET/CT images from 25 pediatric patients (0.5-16 years old) in this retrospective study. Patient images were reconstructed with conventional iterative techniques or BSREM with varied penalization factor (β), at varied acquisition time (45 s, 90 s, 180 s, 300 s) to simulate reduced count density. Two pediatric nuclear medicine physicians reviewed images in random order - blinded to patient, reconstruction method and imaging time - and scored technical quality (noise, spatial resolution, artifacts), clinical quality (image quality of the cortex, basal ganglia and thalamus) and overall diagnostic satisfaction on a 5-point scale.

resultsReconstruction with BSREM improved quality and clinical scores across all count levels, with the greatest benefits in low-count conditions. Image quality scores were greatest at 300-s acquisition times with β=500 (overall; noise; artifacts; image quality of the cortex, basal ganglia and thalamus) or β=200 (spatial resolution). No statistically significant difference in the highest graded reconstruction was observed between imaging at 180 s and 300 s with an appropriately implemented penalization factor (β=350-500), indicating that a reduction in dose or acquisition time is feasible without reduction in diagnostic satisfaction.

conclusionClinical evaluation of pediatric

Indexed as

Positron Emission Tomography Computed TomographyAdolescentChildChild, PreschoolEpilepsyFemaleFluorodeoxyglucose F18HumansImage Interpretation, Computer-AssistedInfantMaleRadiopharmaceuticalsRetrospective StudiesTime FactorsFluorodeoxyglucose F18RadiopharmaceuticalsBrainChildrenComputed tomographyEpilepsyPositron emission tomographyRadiationReconstruction

Identifiers

PMID32125447
OpenAlexW3010452423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.