Evidence map›Paper›PMID 32125020›Full record

ArticleMagnetic resonance in medicine2020

High-fidelity, accelerated whole-brain submillimeter in vivo diffusion MRI using gSlider-spherical ridgelets (gSlider-SR).

Gabriel Ramos-Llordén, Lipeng Ning, Congyu Liao, Rinat Mukhometzianov, Oleg Michailovich, Kawin Setsompop, Yogesh Rathi

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 citations in OpenAlex.

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  8. Imaging neuroscience (Cambridge, Mass.) · 2025
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  9. bioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Gabriel Ramos-LlordénDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4020-705X
Lipeng NingDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Congyu LiaoAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2270-276X
Rinat MukhometzianovDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Oleg MichailovichDepartment of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
Kawin SetsompopAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Yogesh RathiDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Brigham and Women's Hospital · USHarvard University · USUniversity of Waterloo · CA

Funding

Next generation in-vivo diffusion imaging at submillimeter resolutionR01MH116173 · NIMH · STANFORD UNIVERSITY · PI Yogesh Rathi, Kawin Setsompop · 2018 to 2026
$6.2M
NIMH NIH HHS R01 MH116173
6 · The paper itself

Abstract

purposeTo develop an accelerated, robust, and accurate diffusion MRI acquisition and reconstruction technique for submillimeter whole human brain in vivo scan on a clinical scanner.

methodsWe extend the ultra-high resolution diffusion MRI acquisition technique, gSlider, by allowing undersampling in q-space and radiofrequency (RF)-encoding space, thereby dramatically reducing the total acquisition time of conventional gSlider. The novel method, termed gSlider-SR, compensates for the lack of acquired information by exploiting redundancy in the dMRI data using a basis of spherical ridgelets (SR), while simultaneously enhancing the signal-to-noise ratio. Using Monte Carlo simulation with realistic noise levels and several acquisitions of in vivo human brain dMRI data (acquired on a Siemens Prisma 3T scanner), we demonstrate the efficacy of our method using several quantitative metrics.

resultsFor high-resolution dMRI data with realistic noise levels (synthetically added), we show that gSlider-SR can reconstruct high-quality dMRI data at different acceleration factors preserving both signal and angular information. With in vivo data, we demonstrate that gSlider-SR can accurately reconstruct 860 μm diffusion MRI data (64 diffusion directions at

conclusionsgSlider-SR enables whole-brain high angular resolution dMRI at a submillimeter spatial resolution with a dramatically reduced acquisition time, making it feasible to use the proposed scheme on existing clinical scanners.

Indexed as

Diffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedBrainHumansRadio WavesSignal-To-Noise Ratiodenoisingdiffusion MRIgSliderhigh-resolutionsuper-resolution

Identifiers

PMID32125020
PMCPMC9149785
OpenAlexW2973683106

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.