Evidence map›Paper›PMID 32124721›Full record

ArticleThe American journal of tropical medicine and hygiene2020

MiRNA-146a Polymorphism Was Not Associated with Malaria in Southern India.

Welmoed van Loon, Prabhanjan P Gai, Suyamindra S Kulkarni, Rashmi Rasalkar, Konrad Siegert, Jakob Wedam, Archith Boloor, Shantaram Baliga, Arun Kumar, Animesh Jain and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Non-coding RNAs in malaria infection.Wiley interdisciplinary reviews. RNA · 2022
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Welmoed van LoonInstitute of Tropical Medicine and International Health Berlin, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Prabhanjan P GaiInstitute of Tropical Medicine and International Health Berlin, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Suyamindra S KulkarniKarnataka Institute for DNA Research, Dharwad, India.
Rashmi RasalkarKarnataka Institute for DNA Research, Dharwad, India.
Konrad SiegertInstitute of Tropical Medicine and International Health Berlin, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Jakob WedamInstitute of Tropical Medicine and International Health Berlin, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Archith BoloorManipal Academy of Higher Education, Manipal, India.
Shantaram BaligaManipal Academy of Higher Education, Manipal, India.
Arun KumarDistrict Vector Borne Disease Control Programme Office, Mangaluru, India.
Animesh JainManipal Academy of Higher Education, Manipal, India.
Chakrapani MahabalaManipal Academy of Higher Education, Manipal, India.
Damodara ShenoyManipal Academy of Higher Education, Manipal, India.
Rajeshwari DeviWenlock Hospital, Mangaluru, India.
Pramod GaiKarnataka Institute for DNA Research, Dharwad, India.
Frank P MockenhauptInstitute of Tropical Medicine and International Health Berlin, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Freie Universität Berlin · DEKasturba Medical College, MangaloreCharité - Universitätsmedizin Berlin · DEHumboldt-Universität zu Berlin · DEKasturba Medical College, Manipal · INManipal Academy of Higher Education · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro-RNAs (miRNAs) play a crucial role in immune regulation, and a common miRNA-146a polymorphism (rs2910164) increased the odds of falciparum malaria in pregnant African women. Here, we examined whether this association holds true in a different population, that is, 449 mainly male and adult malaria patients and 666 community controls in southwestern India.

Indexed as

AdultCase-Control StudiesFemaleGenetic Predisposition to DiseaseHumansIndiaMalaria, FalciparumMalaria, VivaxMaleMicroRNAsPolymorphism, Single NucleotideMicroRNAsMIRN146 microRNA, human

Identifiers

PMID32124721
PMCPMC7204598
OpenAlexW3009862161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.