Evidence map›Paper›PMID 32124436›Full record

Observational studyDevelopmental medicine and child neurology2020

Anteroposterior balance reactions in children with spastic cerebral palsy.

Jeremy R Crenshaw, Drew A Petersen, Benjamin C Conner, James B Tracy, Jamie Pigman, Henry G Wright, Freeman Miller, Curtis L Johnson, Christopher M Modlesky

Registry-linked trialOpen access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Developmental medicine and child neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07403162 (Effects of Cuevas Medek Exercises on Postural Control and Balance in Children With Spastic Cerebral Palsy), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07403162 nacompletednot on this mapstarted 2026, after this paper: background citation

Effects of Cuevas Medek Exercises on Postural Control and Balance in Children With Spastic Cerebral Palsy

TypeinterventionalSponsorRiphah International UniversityRan2026 to 2026Enrolled54ConditionsSpastic Cerebral Palsy (sCP)ArmsCuevas medek exercises, Conventional Therapy
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jeremy R CrenshawDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.ORCID 0000-0002-5108-3630
Drew A PetersenDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.
Benjamin C ConnerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.ORCID 0000-0002-9567-9989
James B TracyDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.
Jamie PigmanDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.
Henry G WrightDepartment of Physical Therapy, University of Delaware, Newark, DE, USA.
Freeman MillerDepartment of Orthopedics, Nemours A.I. duPont Hospital for Children, Wilmington, DE, USA.
Curtis L JohnsonDepartment of Biomedical Engineering, University of Delaware, Newark, DE, USA.ORCID 0000-0002-7760-131X
Christopher M ModleskyDepartment of Kinesiology, University of Georgia, Athens, GA, USA.ORCID 0000-0003-2654-6311
University of Delaware · USCommunity Health Systems - Dupont Hospital · USDrexel University · USMonmouth University · USUniversity of Arizona · USUniversity of Georgia · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Anjana Narayan Bhat · 2012 to 2026
$67.2M
Pilot Project ProgramP30GM103333 · NIGMS · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2012 to 2016
$5.7M
Effect of vibration on muscle properties, physical activity and balance in children with cerebral palsyR01HD090126 · NICHD · UNIVERSITY OF GEORGIA · PI MODLESKY, CHRISTOPHER M · 2017 to 2022
$3.0M
Eunice Kennedy Shriver National Institute of Child Health and Human Development 1 R01 HD090126NICHD NIH HHS R01 HD090126NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P30 GM103333
6 · The paper itself

Abstract

aimTo compare anterior and posterior standing balance reactions, as measured by single-stepping thresholds, in children with and without spastic cerebral palsy (CP).

methodSeventeen ambulatory children with spastic CP (eight males, nine females) and 28 typically developing children (13 males, 15 females; age range 5-12y, mean [SD] 9y 2mo [2y 3mo]), were included in this cross-sectional, observational study. Balance reaction skill was quantified as anterior and posterior single-stepping thresholds, or the treadmill-induced perturbations that consistently elicited a step in that direction. In order to understand the underlying mechanisms of between-group differences in stepping thresholds, dynamic stability was quantified using the minimum margin of stability. Ankle muscle activation latency, magnitude, and co-contraction were assessed with surface electromyography.

resultsWe observed an age and group interaction for anterior thresholds (p=0.001, partial η

interpretationThe effects of CP on balance reactions are age- and direction-specific. Older typically developing children are more able or willing to withhold a step when unstable. WHAT THIS PAPER ADDS: Children with spastic cerebral palsy have age- and direction-specific balance-reaction impairments. Lower anterior stepping thresholds were observed in older, but not younger children. Older typically developing children withheld a forward step at higher levels of instability. No between-group differences were seen in posterior stepping thresholds.

Indexed as

Age FactorsCerebral PalsyChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMuscle, SkeletalPostural BalanceWalking

Identifiers

PMID32124436
PMCPMC7916524
OpenAlexW3009564979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.