Evidence map›Paper›PMID 32124264›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Body composition and changes in health-related quality of life in older age: a 10-year follow-up of the Helsinki Birth Cohort Study.

Tuija M Mikkola, Hannu Kautiainen, Mikaela B von Bonsdorff, Minna K Salonen, Niko Wasenius, Eero Kajantie, Johan G Eriksson

Open access · hybridAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Tuija M MikkolaFolkhälsan Research Center, Helsinki, Finland. tuija.mikkola@folkhalsan.fi.ORCID http://orcid.org/0000-0003-0885-2788
Hannu KautiainenFolkhälsan Research Center, Helsinki, Finland.
Mikaela B von BonsdorffFolkhälsan Research Center, Helsinki, Finland.
Minna K SalonenFolkhälsan Research Center, Helsinki, Finland.
Niko WaseniusFolkhälsan Research Center, Helsinki, Finland.
Eero KajantiePublic Health Promotion Unit, National Institute for Health and Welfare, Helsinki, Finland.
Johan G ErikssonFolkhälsan Research Center, Helsinki, Finland.
Folkhälsans Forskningscentrum · FIUniversity of Helsinki · FIAgency for Science, Technology and Research · SGFinnish Institute for Health and Welfare · FIKuopio University Hospital · FI

Funding

Diabetestutkimussäätiö -Emil Aaltosen Säätiö -Finska Läkaresällskapet -Horizon 2020 Framework Programme 633595Horizon 2020 Framework Programme 733180Horizon 2020 Framework Programme 733206Lastentautien Tutkimussäätiö -Medicinska Understödsföreningen Liv och Hälsa -Novo Nordisk Fonden -Samfundet Folkhälsan -Seventh Framework Programme 278603Signe ja Ane Gyllenbergin Säätiö -Sigrid Juséliuksen Säätiö -Terveyden Tutkimuksen Toimikunta 126775Terveyden Tutkimuksen Toimikunta 127437Terveyden Tutkimuksen Toimikunta 129255Terveyden Tutkimuksen Toimikunta 129306Terveyden Tutkimuksen Toimikunta 129369Terveyden Tutkimuksen Toimikunta 129907Terveyden Tutkimuksen Toimikunta 130326Terveyden Tutkimuksen Toimikunta 134791Terveyden Tutkimuksen Toimikunta 135072Terveyden Tutkimuksen Toimikunta 263924Terveyden Tutkimuksen Toimikunta 274794
6 · The paper itself

Abstract

purposeMost studies examining the associations between body composition and health-related quality of life (HRQoL) in older age have been cross-sectional and analyzed only fat or lean mass. Hence, it is poorly known whether fat and lean mass are independently associated with subsequent changes in HRQoL. We investigated whether baseline lean and fat mass are associated with changes in HRQoL over a 10-year period in older adults.

methodsWe studied 1044 men and women from the Helsinki Birth Cohort Study (age 57-70 years at baseline). Bioelectrical impedance analysis was used to derive baseline fat mass index (FMI, fat mass/height

resultsWhen controlled for lean mass and adjusted for potential confounders, high baseline FMI was associated with a greater decline in general health (standardized regression coefficient [β] = - 0.13, p = 0.001), physical functioning (β = - 0.11, p = 0.002), role physical (β = - 0.13, p = 0.003), vitality (β = - 0.08, p = 0.027), role emotional (β = - 0.12, p = 0.007), and physical component score (β = - 0.14, p < 0.001). High baseline FMI was also associated with low HRQoL in all physical domains at baseline (β: from - 0.38 to - 0.10). Lean mass was not strongly associated with HRQoL at baseline or change in HRQoL.

conclusionIn older community-dwelling adults, higher fat mass is, independent of lean mass, associated with lower physical HRQoL and greater decline in HRQoL. Prevention of adiposity may contribute to preservation of a good quality of life in older age.

Indexed as

AgedBody CompositionCohort StudiesCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedQuality of LifeTime FactorsAgingBody compositionFat massHealth-related quality of lifeLean massObesity

Identifiers

PMID32124264
PMCPMC7363735
OpenAlexW3009902115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.