Evidence map›Paper›PMID 32124261›Full record

ArticleEndocrine2020

Indeterminate thyroid nodules. The role of

Arnoldo Piccardo, Matteo Puntoni, Marih Dezzana, Gianluca Bottoni, Luca Foppiani, Alessandro Marugo, Ugo Catrambone, Martina Ugolini, Simona Sola, Martina Gatto and 3 more

Abstract read
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In one paragraph

Article in Endocrine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Molecular Diagnostics and [Thyroid : official journal of the American Thyroid Association · 2024
    Trial
  4. [Molecular imaging and biology · 2023
    Trial
  5. [European journal of nuclear medicine and molecular imaging · 2022
    Trial
  6. Article
  7. Enhanced staging of differentiated thyroid carcinoma: integrating [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Article
  9. Article
  10. Role of [Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Arnoldo PiccardoDepartment of Nuclear Medicine, Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy. arnoldo.piccardo@galliera.it.ORCID http://orcid.org/0000-0002-6779-1471
Matteo PuntoniClinical Trial Research Unit, Galliera Hospital, Genoa, Italy.
Marih DezzanaDepartment of Histopathology, Galliera Hospital, Genoa, Italy.
Gianluca BottoniDepartment of Nuclear Medicine, Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Luca FoppianiDepartment of Internal Medicine, Galliera Hospital, Genoa, Italy.
Alessandro MarugoEndocrinology Unit, Galliera Hospital, Genoa, Italy.
Ugo CatramboneDepartment of Surgery, Galliera Hospital, Genoa, Italy.
Martina UgoliniDepartment of Nuclear Medicine, Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Simona SolaDepartment of Histopathology, Galliera Hospital, Genoa, Italy.
Martina GattoDepartment of Nuclear Medicine, Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Giorgio TregliaClinic for Nuclear Medicine and Competence Center for Thyroid Diseases, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Luca Giovanella *Clinic for Nuclear Medicine and Competence Center for Thyroid Diseases, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Pierpaolo Trimboli *Clinic for Nuclear Medicine and Competence Center for Thyroid Diseases, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Ente Ospedaliero Ospedali Galliera · ITEnte Ospedaliero Cantonale · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the reliability of

methodsWe evaluated all patients with thyroid nodules and indeterminate cytology from September 2015 to May 2019; nodules were classified as low risk (TIR3A) and high risk (TIR3B) according to the ICCRTC. Neck ultrasonography features according to EU-TIRADS were re-evaluated and

resultsWe included 111 patients; 67 nodules were classified as TIR3A and 44 as TIR3B. Overall, we found 27 DTCs, 57 NHs and 27 FNs. Among 73 FDG-negative nodules, we found four low-risk papillary thyroid cancers. All follicular thyroid cancers were identified by

conclusion

Indexed as

Thyroid NeoplasmsThyroid NoduleFluorodeoxyglucose F18HumansItalyPositron Emission Tomography Computed TomographyReproducibility of ResultsRisk AssessmentUltrasonographyFluorodeoxyglucose F1818F-FDG PET/CTElderly, ultrasonography risk stratification systemsThyroid cytologyThyroid nodules

Identifiers

PMID32124261
OpenAlexW3009830398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.