Evidence map›Paper›PMID 32124233›Full record

ReviewInternational urology and nephrology2020

Nocardiosis in patients with nephrotic syndrome: a retrospective analysis of 11 cases and a literature review.

Jinzhou Guo, Shijun Li, Shutian Xu, Ling Jiang, Erzhi Gao, Zhihong Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in cellular and infection microbiology · 2021
    Pooled it
  3. Nocardiosis: A Neglected Disease.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020
    Pooled it
  4. Review
  5. Case Report: Pulmonary mixed infection byFrontiers in immunology · 2025
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jinzhou GuoDepartment of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210016, China.
Shijun LiDepartment of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210016, China. lisj8855@163.com.ORCID http://orcid.org/0000-0001-6158-4423
Shutian XuDepartment of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210016, China.
Ling JiangDepartment of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210016, China.
Erzhi GaoDepartment of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210016, China.
Zhihong LiuDepartment of Nephrology, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210016, China.
Nanjing General Hospital of Nanjing Military Command · CN

Funding

the National Nature Science Foundation of China 81270799the National Science and Technology Infrastructure Program of China 2013BAI09B04the National Science and Technology Infrastructure Program of China 2015BAI12B05
6 · The paper itself

Abstract

objectivesWe evaluated the clinical manifestations and outcomes of nocardiosis, a rare opportunistic infection that occurs in patients with nephrotic syndrome.

methodsThe records of NS patients with nocardiosis in a single hospital during 2000-2019 were retrieved and studied in detail.

resultsEleven patients were included. The mean time to develop nocardiosis after glucocorticoid therapy was 11.5 ± 14.8 months. Most patients had fever, elevated white blood cell counts and C-reactive protein, whereas procalcitonin levels were normal or slightly elevated in 91% (10/11) patients, except one patient suffered from septic shock. Nine patients were tested for CD4

conclusionsNS patients can develop immunodeficiency after treatment with glucocorticoid and immunosuppressants. In cases where patients develop systemic multiple abscesses, or lung images reveal isolated or scattered nodules and masses that are subpleural or close to the hilum, nocardial infection should be considered. Early diagnosis and specific treatment may improve patient outcomes.

Indexed as

AbscessAdultAgedAnti-Bacterial AgentsCarbapenemsCD4 Lymphocyte CountC-Reactive ProteinDrug Therapy, CombinationFemaleFeverGlucocorticoidsHumansLung DiseasesMaleMiddle AgedNephrotic SyndromeAnti-Bacterial AgentsCarbapenemsC-Reactive ProteinGlucocorticoidsProcalcitoninTrimethoprim, Sulfamethoxazole Drug CombinationCell-mediated immunityClinical manifestationsNephrotic syndromeNocardiosisProcalcitonin

Identifiers

PMID32124233
OpenAlexW3009083519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.