Evidence map›Paper›PMID 32124112›Full record

SynthesisTechniques in coloproctology2020

Systematic review and meta-analysis comparing primary resection and anastomosis versus Hartmann's procedure for the management of acute perforated diverticulitis with generalised peritonitis.

O K Ryan, Éanna J Ryan, B Creavin, M R Boland, M E Kelly, D C Winter

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Techniques in coloproctology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Diverticulitis, surgery, evidence-based medicine, and the Steve Jobs' dots: a narrative review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Evidence-based treatment strategies for acute diverticulitis.International journal of colorectal disease · 2021
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

O K RyanUniversity College Dublin School of Medicine and Medical Science, Dublin, Ireland.ORCID 0000-0003-2750-4607
Éanna J RyanUniversity College Dublin School of Medicine and Medical Science, Dublin, Ireland. eannaryan@rcsi.com.
B CreavinUniversity College Dublin School of Medicine and Medical Science, Dublin, Ireland.
M R BolandCentre for Colorectal Disease, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
M E KellyUniversity College Dublin School of Medicine and Medical Science, Dublin, Ireland.
D C WinterUniversity College Dublin School of Medicine and Medical Science, Dublin, Ireland.
University College Dublin · IESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical strategies for acute perforated diverticulitis with generalised peritonitis remain controversial. This study aimed to meta-analyse trials comparing primary resection and anastomosis (PRA) to Hartmann's procedure (HP) for Hinchey III/IV diverticulitis.

methodsA systematic literature search was conducted to identify observational studies and randomised control trials (RCTs) of patients with Hinchey III/IV diverticulitis undergoing sigmoidectomy that compared PRA to HP. The methodological quality of the included studies was assessed systematically (Newcastle-Ottawa, Jadad and Cochrane risk of bias scores) and a meta-analysis was performed.

resultsAfter removal of duplicates, 12 studies including 4 RCTs were identified. The analysis included 918 patients, of whom 367 (39.98%) underwent PRA. Both the initial stoma rate (risk ratio [RR] persistent stoma 0.43, 95% confidence interval [CI] 0.26, 0.71, p = 0.001; I

conclusionsThis meta-analysis demonstrates that PRA used in the management of haemodynamically stable patients with Hinchey grade III/IV diverticulitis leads to a lower overall persistent stoma rate, with reduced morbidity compared with the traditional management.

Indexed as

DiverticulitisDiverticulitis, ColonicIntestinal PerforationPeritonitisAnastomosis, SurgicalColostomyHumansTreatment OutcomeDiverticulitisHartmann’s procedureMeta analysisPrimary resection and anastomosisStoma reversal

Identifiers

PMID32124112
OpenAlexW3009618328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.