Evidence map›Paper›PMID 32124100›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2020

X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser.

Elizabeth M Bolitho, Carlos Sanchez-Cano, Huaiyi Huang, Ian Hands-Portman, Matthew Spink, Paul D Quinn, Maria Harkiolaki, Peter J Sadler

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes.Journal of the American Chemical Society · 2021
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Elizabeth M BolithoDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0003-1658-0866
Carlos Sanchez-CanoDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK. csanchez@cicbiomagune.es.ORCID http://orcid.org/0000-0002-9522-0019
Huaiyi HuangDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0002-2091-7954
Ian Hands-PortmanSchool of Life Sciences, University of Warwick, Gibbet Hill Campus, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0002-8895-2342
Matthew SpinkDiamond House, Harwell Science and Innovation Campus, Fermi Ave, Didcot, OX11 0DE, UK.ORCID http://orcid.org/0000-0003-1379-6020
Paul D QuinnDiamond House, Harwell Science and Innovation Campus, Fermi Ave, Didcot, OX11 0DE, UK.ORCID http://orcid.org/0000-0002-7607-4271
Maria HarkiolakiDiamond House, Harwell Science and Innovation Campus, Fermi Ave, Didcot, OX11 0DE, UK. maria.harkiolaki@diamond.ac.uk.ORCID http://orcid.org/0000-0001-8091-9057
Peter J SadlerDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK. p.j.sadler@warwick.ac.uk.ORCID http://orcid.org/0000-0001-9160-1941
Diamond Light Source · GBUniversity of Warwick · GB

Funding

Cancer Research UK C53561/A19933Wellcome TrustWellcome Trust 107691/Z/15/Z
6 · The paper itself

Abstract

The organoiridium complex Ir[(C,N)

Indexed as

CryopreservationPhotochemotherapyAntineoplastic AgentsCell ProliferationCoordination ComplexesDrug Screening Assays, AntitumorHumansIridiumMaleMitochondriaMolecular ConformationPC-3 CellsPhotosensitizing AgentsProstatic NeoplasmsTomography, X-Ray ComputedAntineoplastic AgentsCoordination ComplexesIridiumPhotosensitizing AgentsAnticancer metallodrugsCryo-soft X-ray tomographyIridium complexesPhosphorescencePhotodynamic therapyX-ray microscopy

Identifiers

PMID32124100
PMCPMC7082392
OpenAlexW3009168242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.