SynthesisWorld journal of urology2020
Early recovery after surgery for radical cystectomy: comprehensive assessment and meta-analysis of existing protocols.
Synthesis in World journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- A meta-analysis of the implementation of enhanced recovery after surgery pathways in anterior cervical spine surgery for degenerative cervical spine diseases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Pooled it
- Comparison of Robotic vs Open Cystectomy: A Systematic Review.Bladder cancer (Amsterdam, Netherlands) · 2023Pooled it
- Short-term morbidity and mortality following radical cystectomy: a systematic review.BMJ open · 2021Pooled it
- Exploring the Role of the Nurse Case Manager in the Care Experience of Patients Undergoing Radical Cystectomy: A Qualitative Study.Nursing open · 2026Article
- Association of ERAS protocol adherence with complications and readmissions following open radical cystectomy: a pilot study from an ERAS Society-qualified centre.International urology and nephrology · 2026Article
- Intraoperative pelvic drain placement and postoperative outcomes following robot-assisted radical cystectomy: a contemporary NSQIP analysis.Journal of robotic surgery · 2026Article
- Enhanced recovery after radical cystectomy for bladder cancer: a prospective observational case -control study.BMC urology · 2026Observational
- The Diagnosis and Management of Urosymphyseal Fistula with Pubic Osteomyelitis.Current urology reports · 2025Review
- The Global RAdical Cystectomy Evaluation and Management (GRACEM) pathway: single-centre prospective observational cohort study protocol.BJUI compass · 2025Article
- National Surgical Quality Improvement Program audit of contemporary perioperative care for radical cystectomy.BJU international · 2025Article
- Integrated enhanced recovery after surgery protocol in radical cystectomy for bladder tumour-A retroprospective study.BJUI compass · 2024Article
- Impact of a kidney-adjusted ERASLangenbeck's archives of surgery · 2024Article
- BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer: Current Treatment Landscape and Novel Emerging Molecular Targets.International journal of molecular sciences · 2023Review
- Robot-assisted laparoscopic radical cystectomy with intracorporeal ileal conduit diversion versus open radical cystectomy with ileal conduit for bladder cancer in an ERAS setup (BORARC): protocol for a single-centre, double-blinded, randomised feasibility study.Pilot and feasibility studies · 2023Article
- The effect of the enhanced recovery after surgery program on radical cystectomy: a meta-analysis and systematic review.Frontiers in surgery · 2023Review
- Neobladder "Function": Tips and Tricks for Surgery and Postoperative Management.Life (Basel, Switzerland) · 2022Review
- Association between use of ERAS protocols and complications after radical cystectomy.World journal of urology · 2022Article
- Essential elements of anaesthesia practice in ERAS programs.World journal of urology · 2022Article
- Current application of the enhanced recovery after surgery protocol for patients undergoing radical cystectomy: lessons learned from European excellence centers.World journal of urology · 2022Article
- High time for a holistic approach to perioperative care in urological surgery.World journal of urology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDifferent enhanced recovery after surgery (ERAS) protocols (EP) for radical cystectomy (RC) have been published. Protocols highly differ in number of included items and specific measures. MATERIALS AND
methodsA systematic review and meta-analysis on EPs in RC were performed using the databases MedLine, Cochrane Library, Web of science, and Google Scholar. The specific ERAS measures of the protocols were extracted, analyzed, and compared. Pooling of available outcome data was performed for length of stay, complications, readmission rate, and time to defecation.
resultsThe search yielded a total of 860 studies of which 25 studies were included in qualitative and 22 in quantitative analysis. Oral bowel preparation (BP) was omitted in 24/25 (96%) EPs, optimized fluid management was administered in 22/25 (88%) EPs and early mobilization (postoperative day 1) in 21/25 (84%). Gum chewing (n = 12, 46%), metoclopramide (n = 11, 44%), and alvimopan (n = 6, 24%) were the most common measures to prevent postoperative ileus. Our meta-analysis revealed a significant benefit in favor of EPs for the outcome parameters length of stay [mean difference (MD) - 3.46 d, 95% confidence interval (CI) - 4.94 to - 1.98, p < 0.01], complications [Odds ratio (OR) = 0.76, 95% CI 0.61-0.94, p = 0.01] and time to defecation (MD - 1.37 d, 95% CI - 2.06 to - 0.69, p < 0.01). Readmission rate did not show a significant difference (OR = 0.73, 95% CI 0.52-1.03, p = 0.07).
conclusionCurrent EPs focus on omitting oral BP, early mobilization, and optimized fluid management while they differ in methods preventing postoperative ileus. Our meta-analysis revealed a benefit in introducing these protocols into clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.