Evidence map›Paper›PMID 32123984›Full record

ArticleCurrent microbiology2020

Production of Mannosylerythritol Lipids (MELs) to be Used as Antimicrobial Agents Against S. aureus ATCC 6538.

Chiara Ceresa, Simon Hutton, Marta Lajarin-Cuesta, Robert Heaton, Iain Hargreaves, Letizia Fracchia, Mayri A Díaz De Rienzo

Open access · hybridAbstract read
In one paragraph

Article in Current microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chiara CeresaDepartment of Pharmaceutical Sciences, Università del Piemonte Orientale "A. Avogadro", 28100, Novara, Italy.
Simon HuttonSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building 10.05C, Byrom Street, Liverpool, L3 3AF, UK.
Marta Lajarin-CuestaSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building 10.05C, Byrom Street, Liverpool, L3 3AF, UK.
Robert HeatonSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building 10.05C, Byrom Street, Liverpool, L3 3AF, UK.
Iain HargreavesSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building 10.05C, Byrom Street, Liverpool, L3 3AF, UK.
Letizia FracchiaDepartment of Pharmaceutical Sciences, Università del Piemonte Orientale "A. Avogadro", 28100, Novara, Italy.
Mayri A Díaz De RienzoSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building 10.05C, Byrom Street, Liverpool, L3 3AF, UK. m.a.diaz@ljmu.ac.uk.ORCID http://orcid.org/0000-0002-1586-0666
Liverpool John Moores University · GBUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

Compagnia di San Paolo Excellent Young PI-2014 CallLiverpool John Moores University ECR Fellowship 2017-2018Università degli Studi del Piemonte Orientale Bando Fondazione CRT, Id. 393
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a current major health issue, both for the high rates of resistance observed in bacteria that cause common infections and for the complexity of the consequences of AMR. Pathogens like Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Mycobacterium tuberculosis among others are clear examples of antibiotic-resistant threats. Biosurfactants have recently emerged as a potential new generation of anti-adhesive and anti-biofilm agents; mannosylerythritol lipids (MELs) are biosurfactants produced by a range of fungi. A range of structural variants of MELs can be formed and the proportion of each isomer in the fermentation depends on the yeast used, the carbon substrate used for growth and the duration of the fermentation. In order to allow assessment of the possible functions of MELs as antimicrobial molecules, small quantities of MEL were produced by controlled fermentation. Fermentations of the yeast Pseudozyma aphidis using rapeseed oil as a carbon source yielded up to 165 g

Indexed as

FermentationAnti-Infective AgentsBasidiomycotaBiofilmsBiomassCulture MediaGlycolipidsRapeseed OilStaphylococcus aureusSurface-Active AgentsAnti-Infective AgentsCulture MediaGlycolipidsmannosylerythritol lipidRapeseed OilSurface-Active Agents

Identifiers

PMID32123984
PMCPMC7334285
OpenAlexW3010604335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.