Evidence map›Paper›PMID 32123973›Full record

Trial reportPsychopharmacology2020

Acute effects of oxytocin in music performance anxiety: a crossover, randomized, placebo-controlled trial.

Alini D V Sabino, Marcos Hortes N Chagas, Flávia L Osório

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alini D V SabinoMedical School of Ribeirão Preto, São Paulo University, Avenida dos Bandeirantes, 3900, Ribeirão Preto, SP, 14048-900, Brazil.
Marcos Hortes N ChagasCenter for Biological and Health Sciences, Federal University of São Carlos, São Carlos, Brazil.
Flávia L OsórioMedical School of Ribeirão Preto, São Paulo University, Avenida dos Bandeirantes, 3900, Ribeirão Preto, SP, 14048-900, Brazil. flaliosorio@gmail.com.ORCID http://orcid.org/0000-0002-7621-1790
National Council for Scientific and Technological Development · BRUniversidade Federal de São Carlos · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Process 155367/2016-1Conselho Nacional de Desenvolvimento Científico e Tecnológico Process 301321/2016-7Fundação de Amparo à Pesquisa do Estado de São Paulo Process no. 15/02848-2
6 · The paper itself

Abstract

rationaleIndividuals with music performance anxiety (MPA) present physical, behavioral, and cognitive manifestations of anxiety, in addition to information processing deficits, especially in facial emotion recognition (FER).

objectivesTo assess the effects of a single dose of intranasal oxytocin (24 IU) on FER in a sample of musicians with high and low MPA (primary outcome), as well as indicators of mood/anxiety and self-assessed performance (secondary outcomes).

methodsCrossover, randomized, double-blind, placebo-controlled trial involving 43 male musicians with different levels of MPA. Participants completed a static facial emotion recognition task and self-rated mood and performance scales. Data were analyzed using ANOVA 2 × 0 for crossover trials and the Omnibus test (measure of separability between intervention and carryover effects).

resultsOnly musicians with high MPA treated with oxytocin had a higher accuracy in the recognition of happiness (p < 0.03; d > 0.72). No effects of oxytocin were found on mood indicators or on self-perceived performance, regardless of MPA level.

conclusionsThe results indicate possible benefits of the acute treatment with oxytocin in MPA, which may improve the management of this common and disabling condition that affects professional musicians. The appropriate perception of positive feedback may increase confidence and feelings of social acceptance, reducing symptoms associated with the condition. The lack of effects on mood/anxiety and cognition may be explained by the context-dependent characteristic of the effects of oxytocin, since the experiment did not represent an actual situation of social threat.

trial registrationBrazilian Clinical Trials Registry (Registro Brasileiro de Ensaios Clínicos): No. RBR-9cph2q.

Indexed as

Administration, IntranasalAdultBrazilCross-Over StudiesDouble-Blind MethodEmotionsFacial ExpressionFacial RecognitionHumansMaleMusicOxytocinPerformance AnxietyTreatment OutcomeOxytocinCognitionFacial emotionMoodMusic performance anxietyOxytocin

Identifiers

PMID32123973
OpenAlexW3010133508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.