ArticleBioactive materials2020
Design biodegradable Zn alloys: Second phases and their significant influences on alloy properties.
Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Degradation behavior and biological properties of a novel biodegradable zinc alloy biliary stent.Bioactive materials · 2026Article
- Simultaneously improve mechanical properties and osteogenic properties of biodegradable Zn alloys by refining grain sizes to sub-micrometers.Scientific reports · 2026Article
- Effect of Mn content on the corrosion behavior and biocompatibility of biodegradable Zn-Mn alloys.Scientific reports · 2025Article
- The biological effects of copper alloying in Zn-based biodegradable arterial implants.Biomaterials advances · 2025Article
- Biodegradable zinc alloys with high strength and suitable mechanical integrity as bone repair metals.Scientific reports · 2024Article
- Highly plastic Zn-0.3Ca alloy for guided bone regeneration membrane: Breaking the trade-off between antibacterial ability and biocompatibility.Bioactive materials · 2024Article
- Fabrication and performance of Zinc-based biodegradable metals: From conventional processes to laser powder bed fusion.Bioactive materials · 2024Review
- Review
- 3D Printing of a Porous Zn-1Mg-0.1Sr Alloy Scaffold: A Study on Mechanical Properties, Degradability, and Biosafety.Journal of functional biomaterials · 2024Article
- Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms.Materials today. Bio · 2024Review
- Insights into the biocompatibility of biodegradable metallic molybdenum for cardiovascular applications-a critical review.Frontiers in bioengineering and biotechnology · 2024Review
- Fucoidan- and Ciprofloxacin-Doped Plasma-Activated Polymer Coatings on Biodegradable Zinc: Hemocompatibility and Drug Release.ACS omega · 2023Article
- [Research status and development of biodegradable zinc alloy as orthopedics implant].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- SystematicBioactive materials · 2023Article
- Development, Processing and Aging of Novel Zn-Ag-Cu Based Biodegradable Alloys.Materials (Basel, Switzerland) · 2023Article
- Three-Dimensional Printing of Poly-L-Lactic Acid Composite Scaffolds with Enhanced Bioactivity and Controllable Zn Ion Release Capability by Coupling with Carbon-ZnO.Bioengineering (Basel, Switzerland) · 2023Article
- In vitro cytocompatibility and antibacterial studies on biodegradable Zn alloys supplemented by a critical assessment of direct contact cytotoxicity assay.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Recent Developments in Zn-Based Biodegradable Materials for Biomedical Applications.Journal of functional biomaterials · 2022Review
- Microstructural and Mechanical Characterization of Newly Developed Zn-Mg-CaO Composite.Materials (Basel, Switzerland) · 2022Article
- Laser Additive Manufacturing of Zinc Targeting for Biomedical Application.International journal of bioprinting · 2022Review
Corrections and comments
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Alloying combined with plastic deformation processing is widely used to improve mechanical properties of pure Zn. As-cast Zn and its alloys are brittle. Beside plastic deformation processing, no effective method has yet been found to eliminate the brittleness and even endow room temperature super-ductility. Second phase, induced by alloying, not only largely determines the ability of plastic deformation, but also influences strength, corrosion rate and cytotoxicity. Controlling second phase is important for designing biodegradable Zn alloys. In this review, knowledge related to second phases in biodegradable Zn alloys has been analyzed and summarized, including characteristics of binary phase diagrams, volume fraction of second phase in function of atomic percentage of an alloying element, and so on. Controversies about second phases in Zn-Li, Zn-Cu and Zn-Fe systems have been settled down, which benefits future studies. The effects of alloying elements and second phases on microstructure, strength, ductility, corrosion rate and cytotoxicity have been neatly summarized. Mg, Mn, Li, Cu and Ag are recommended as the major alloying elements, owing to their prominent beneficial effects on at least one of the above properties. In future, synergistic effects of these elements should be more thoroughly investigated. For other nutritional elements, such as Fe and Ca, refining second phase is a matter of vital concern.
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